Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2982608..2983883 Replicon chromosome
Accession NZ_AP014522
Organism Pseudomonas protegens Cab57

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PPC_RS13670 Protein ID WP_041117840.1
Coordinates 2983284..2983883 (+) Length 200 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PPC_RS13665 Protein ID WP_041120629.1
Coordinates 2982608..2983165 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPC_RS13635 2978124..2978354 + 231 WP_041117828.1 DUF3079 domain-containing protein -
PPC_RS13640 2978400..2979050 + 651 WP_041117830.1 DUF2239 family protein -
PPC_RS13645 2979138..2979758 + 621 WP_041117832.1 LysE family translocator -
PPC_RS13650 2979804..2980391 - 588 WP_041117834.1 inclusion body family protein -
PPC_RS13655 2980802..2981989 + 1188 WP_041117836.1 PrpF protein -
PPC_RS13660 2982077..2982418 - 342 WP_041117838.1 low molecular weight protein tyrosine phosphatase family protein -
PPC_RS13665 2982608..2983165 + 558 WP_041120629.1 helix-turn-helix domain-containing protein Antitoxin
PPC_RS13670 2983284..2983883 + 600 WP_041117840.1 HD domain-containing protein Toxin
PPC_RS13675 2984097..2986277 + 2181 WP_041117842.1 catalase/peroxidase HPI -
PPC_RS13680 2986339..2987025 - 687 WP_041117844.1 hypothetical protein -
PPC_RS13685 2986985..2987605 - 621 WP_011060988.1 hypothetical protein -
PPC_RS13690 2987672..2988100 - 429 WP_041117846.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-47)


Sequences

Toxin        


Download         Length: 200 a.a.        Molecular weight: 22404.18 Da        Isoelectric Point: 5.8807

>T30630 WP_041117840.1 NZ_AP014522:2983284-2983883 [Pseudomonas protegens Cab57]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPNKSQQERDDLQYLARALDAPARQCLLDLWDEYEGAASAEARTVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFLALRQQIDADTQRRLDAQAQAAGQHRLR

Download         Length: 600 bp

>T30630 NZ_AP014522:2983284-2983883 [Pseudomonas protegens Cab57]
ATGAACAGTGAACTTCTCAGCGGCCGCCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTACTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAGCTGTGCATCGTCCACGACTTGGGGGAGGCCATTCACGGCGACATCCCG
GCGGTGGCCCAGGCGGCGCACCCGAACAAGAGCCAGCAGGAACGCGACGACCTGCAATACCTCGCCCGGGCCCTGGACGC
TCCGGCCCGCCAATGCCTGTTGGATCTGTGGGATGAATACGAGGGCGCCGCCAGCGCCGAGGCGCGCACGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGACGCCAGCCCACTGTTCCTGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGGTCAGCATCGGCTGCGCTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20412.38 Da        Isoelectric Point: 7.7603

>AT30630 WP_041120629.1 NZ_AP014522:2982608-2983165 [Pseudomonas protegens Cab57]
MSAALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGRNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT30630 NZ_AP014522:2982608-2983165 [Pseudomonas protegens Cab57]
ATGTCCGCAGCCTTATTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAACAGCA
GCACGCCGCCGAGCTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAGGCCATGGAACCGGCAG
AGCGTGCGCGTCTGGAACAACTGCTGGCAGCCAACCTCAGCGCCGCCGCCGATCAGGCCCTGGCGCGGCTGGTGAATGAC
AGCCCGCGTGCCGTGCACCTGGTTTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGGGCAGTTCGG
CGTGCCCTTGAGCGAGCTGCTGGGCCAATCCCTGTGGGGCTTCTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTGCTGGCGCCGCCGTCCCTGGAATTCTTCAGCGGCCGCAACGATTCGGCCATCGTACCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References