Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 757049..757645 Replicon chromosome
Accession NZ_AP014522
Organism Pseudomonas protegens Cab57

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PPC_RS03315 Protein ID WP_041115684.1
Coordinates 757343..757645 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PPC_RS03310 Protein ID WP_041115682.1
Coordinates 757049..757339 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPC_RS03290 753320..755452 - 2133 WP_041115674.1 TonB-dependent copper receptor -
PPC_RS03295 755541..755951 - 411 WP_041115676.1 DUF2946 domain-containing protein -
PPC_RS03300 756007..756486 - 480 WP_171820738.1 copper chaperone PCu(A)C -
PPC_RS03305 756551..756949 - 399 WP_041115680.1 DUF2946 domain-containing protein -
PPC_RS03310 757049..757339 - 291 WP_041115682.1 putative addiction module antidote protein Antitoxin
PPC_RS03315 757343..757645 - 303 WP_041115684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PPC_RS03320 757828..758556 - 729 WP_041115686.1 cobalt-precorrin-6A reductase -
PPC_RS03325 758553..759650 - 1098 WP_041115688.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PPC_RS03330 759744..760958 - 1215 WP_041115690.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
PPC_RS03335 761097..762410 + 1314 WP_041115692.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-97)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11645.41 Da        Isoelectric Point: 10.6580

>T30628 WP_041115684.1 NZ_AP014522:c757645-757343 [Pseudomonas protegens Cab57]
MFVFEQTQAFTHWLLRLKDPQGKPRVLARIRAAQLGRFGDCEPVGEGVYEMRIHRGPGYRVYFSRRDTVIYLLLIGGDKS
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T30628 NZ_AP014522:c757645-757343 [Pseudomonas protegens Cab57]
ATGTTCGTCTTTGAGCAGACTCAGGCGTTTACCCACTGGCTGCTACGCCTAAAAGATCCCCAGGGAAAACCCCGCGTGCT
GGCCCGGATCAGGGCGGCGCAACTGGGCCGTTTCGGCGACTGCGAACCCGTGGGCGAAGGTGTCTATGAAATGCGCATCC
ATCGCGGCCCCGGCTACCGGGTGTACTTCTCGCGCCGGGACACTGTGATCTACCTGTTGCTGATCGGCGGTGACAAGAGC
ACCCAGAGACGCGATATCCAACGCGCCAGGCAACTGGCCCATGACCTCAAGAGCGAGGGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10462.03 Da        Isoelectric Point: 5.8268

>AT30628 WP_041115682.1 NZ_AP014522:c757339-757049 [Pseudomonas protegens Cab57]
MRTPVTRFDAAEYLKTPEDMVAYLDACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKSLGSQGNPEFATI
IKVMKALGLKLHVSLA

Download         Length: 291 bp

>AT30628 NZ_AP014522:c757339-757049 [Pseudomonas protegens Cab57]
ATGCGCACCCCAGTGACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTGGCCTACCTCGACGCCTG
CTTCGAGGAAGACACCGGCGACGGCGTGCTGATCCGCGCCGCACTCAACGACATCGCCCGCGCCCGCGGCATGACCCAGG
TCGCCCGTGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGTCCCTGGGCAGCCAGGGCAATCCCGAGTTCGCGACTATC
ATCAAGGTCATGAAGGCACTGGGACTCAAGCTTCACGTCAGCCTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References