30445

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4194932..4195497 Replicon chromosome
Accession NC_023150
Organism Rhodococcus pyridinivorans SB3094

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Y013_RS19105 Protein ID WP_024102981.1
Coordinates 4195219..4195497 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Y013_RS19100 Protein ID WP_006551856.1
Coordinates 4194932..4195222 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y013_RS19075 4190166..4190767 + 602 Protein_3807 TetR/AcrR family transcriptional regulator -
Y013_RS19080 4190764..4191192 + 429 WP_024102975.1 HIT family protein -
Y013_RS19085 4191197..4192798 + 1602 WP_024102976.1 L-lactate permease -
Y013_RS19090 4192875..4193903 + 1029 WP_024102977.1 Dyp-type peroxidase -
Y013_RS19095 4193900..4194718 + 819 WP_024102978.1 bacteriocin family protein -
Y013_RS19100 4194932..4195222 + 291 WP_006551856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Y013_RS19105 4195219..4195497 + 279 WP_024102981.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Y013_RS19110 4195554..4196033 - 480 WP_024102982.1 MarR family transcriptional regulator -
Y013_RS19115 4196092..4196841 - 750 WP_024102983.1 cutinase family protein -
Y013_RS19120 4196991..4197653 - 663 WP_024102984.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
Y013_RS19125 4197774..4198604 + 831 WP_024102985.1 SDR family oxidoreductase -
Y013_RS19130 4198649..4199620 + 972 WP_006551850.1 phosphotriesterase -
Y013_RS19135 4199656..4200375 - 720 WP_041803971.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10268.82 Da        Isoelectric Point: 10.2002

>T30445 WP_024102981.1 NC_023150:4195219-4195497 [Rhodococcus pyridinivorans SB3094]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T30445 NC_023150:4195219-4195497 [Rhodococcus pyridinivorans SB3094]
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
GGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAATCCGAAGCGGGTGGGGAAGCCGTTGAATCCTC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATTTCGCACCGTGCCGATGCGTATCGATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT30445 WP_006551856.1 NC_023150:4194932-4195222 [Rhodococcus pyridinivorans SB3094]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT30445 NC_023150:4194932-4195222 [Rhodococcus pyridinivorans SB3094]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGAGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References