Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
Location | 143765..144270 | Replicon | chromosome |
Accession | NC_023149 | ||
Organism | Pseudomonas aeruginosa SCV20265 |
Toxin (Protein)
Gene name | parE | Uniprot ID | V6A7K8 |
Locus tag | SCV20265_RS00635 | Protein ID | WP_003083773.1 |
Coordinates | 143765..144046 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A1C7BDS9 |
Locus tag | SCV20265_RS00640 | Protein ID | WP_003083775.1 |
Coordinates | 144043..144270 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SCV20265_RS00610 | 139016..140365 | + | 1350 | WP_003142411.1 | C4-dicarboxylate transporter DctA | - |
SCV20265_RS00615 | 140414..141100 | + | 687 | WP_003083762.1 | FadR family transcriptional regulator | - |
SCV20265_RS00620 | 141201..141935 | + | 735 | WP_003117208.1 | GntR family transcriptional regulator | - |
SCV20265_RS00625 | 142139..142525 | + | 387 | WP_014602345.1 | aegerolysin family protein | - |
SCV20265_RS00630 | 142557..143465 | - | 909 | WP_023122914.1 | LysR family transcriptional regulator | - |
SCV20265_RS00635 | 143765..144046 | - | 282 | WP_003083773.1 | type II toxin-antitoxin system toxin ParE | Toxin |
SCV20265_RS00640 | 144043..144270 | - | 228 | WP_003083775.1 | CopG family ribbon-helix-helix protein | Antitoxin |
SCV20265_RS00645 | 144446..145066 | - | 621 | WP_003101226.1 | hypothetical protein | - |
SCV20265_RS00650 | 145167..145667 | + | 501 | WP_003101228.1 | LEA type 2 family protein | - |
SCV20265_RS00655 | 145740..146081 | + | 342 | WP_003101229.1 | alkylphosphonate utilization protein | - |
SCV20265_RS00660 | 146163..147590 | - | 1428 | WP_003083784.1 | GABA permease | - |
SCV20265_RS00665 | 147759..149252 | - | 1494 | WP_003083788.1 | CoA-acylating methylmalonate-semialdehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10462.19 Da Isoelectric Point: 10.0435
>T30436 WP_003083773.1 NC_023149:c144046-143765 [Pseudomonas aeruginosa SCV20265]
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
Download Length: 282 bp
>T30436 NC_023149:c144046-143765 [Pseudomonas aeruginosa SCV20265]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8556.58 Da Isoelectric Point: 5.5740
>AT30436 WP_003083775.1 NC_023149:c144270-144043 [Pseudomonas aeruginosa SCV20265]
MSTVVSFRADDALVAALDELARATHRDRPYHLRQALAQYLERQQWQVAAIDEGLADANAGRLLEHTEIEKRWGLQ
MSTVVSFRADDALVAALDELARATHRDRPYHLRQALAQYLERQQWQVAAIDEGLADANAGRLLEHTEIEKRWGLQ
Download Length: 228 bp
>AT30436 NC_023149:c144270-144043 [Pseudomonas aeruginosa SCV20265]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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