Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 123428..124458 | Replicon | plasmid pGal_B134 |
| Accession | NC_023148 | ||
| Organism | Phaeobacter gallaeciensis DSM 26640 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | GAL_RS20040 | Protein ID | WP_007803220.1 |
| Coordinates | 123428..123997 (-) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | V9WPQ5 |
| Locus tag | GAL_RS20045 | Protein ID | WP_007803221.1 |
| Coordinates | 123994..124458 (-) | Length | 155 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GAL_RS20015 | 119002..119514 | - | 513 | Protein_128 | IS110 family transposase | - |
| GAL_RS20020 | 119586..120377 | - | 792 | WP_007803213.1 | TniQ family protein | - |
| GAL_RS20025 | 120374..121252 | - | 879 | WP_007803215.1 | TniB family NTP-binding protein | - |
| GAL_RS20030 | 121343..122275 | - | 933 | WP_007803217.1 | IS5-like element ISRhba5 family transposase | - |
| GAL_RS20035 | 122527..123369 | + | 843 | WP_007803218.1 | hypothetical protein | - |
| GAL_RS20040 | 123428..123997 | - | 570 | WP_007803220.1 | PIN domain-containing protein | Toxin |
| GAL_RS20045 | 123994..124458 | - | 465 | WP_007803221.1 | excisionase family DNA-binding protein | Antitoxin |
| GAL_RS20050 | 124608..125624 | - | 1017 | WP_024099414.1 | HTH DNA-binding protein | - |
| GAL_RS20055 | 125769..127403 | + | 1635 | WP_024099415.1 | Mu transposase C-terminal domain-containing protein | - |
| GAL_RS20060 | 127405..128286 | + | 882 | WP_024099416.1 | TniB family NTP-binding protein | - |
| GAL_RS22015 | 128340..129317 | + | 978 | WP_158524451.1 | TniQ family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..133621 | 133621 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21163.39 Da Isoelectric Point: 5.2804
>T30435 WP_007803220.1 NC_023148:c123997-123428 [Phaeobacter gallaeciensis DSM 26640]
MSQYTVLFDANVLYPAPMRDALMQLAVTDLFKAKWTADIHREWIDALLRNEPHRERAALERTRDLMDRATRDCLVTGYEA
LVPALTLPDPDDRHVLAAAIVGRCDAIVTQNLKDFPPAALAPFGIETQHPDDFFRNQLSLAPGLVCSALRKVRARLKNPL
KSVDEYLAILTQQGLVATVADLEQFADLL
MSQYTVLFDANVLYPAPMRDALMQLAVTDLFKAKWTADIHREWIDALLRNEPHRERAALERTRDLMDRATRDCLVTGYEA
LVPALTLPDPDDRHVLAAAIVGRCDAIVTQNLKDFPPAALAPFGIETQHPDDFFRNQLSLAPGLVCSALRKVRARLKNPL
KSVDEYLAILTQQGLVATVADLEQFADLL
Download Length: 570 bp
>T30435 NC_023148:c123997-123428 [Phaeobacter gallaeciensis DSM 26640]
ATGAGCCAGTACACGGTCCTGTTCGATGCGAACGTCCTTTATCCCGCGCCGATGCGCGATGCACTGATGCAGTTGGCGGT
CACAGACCTTTTCAAGGCCAAGTGGACGGCCGATATCCATCGGGAGTGGATTGATGCGCTTCTGCGCAATGAACCTCATC
GGGAGCGCGCCGCGCTGGAACGAACTCGCGACTTGATGGACAGGGCCACACGCGACTGTCTGGTCACCGGCTACGAGGCA
TTGGTGCCGGCCCTAACACTGCCGGACCCTGACGATCGGCACGTTCTGGCGGCGGCAATCGTTGGGCGCTGTGACGCGAT
CGTCACGCAGAACCTGAAGGACTTCCCACCAGCGGCACTTGCGCCCTTTGGCATCGAGACCCAACACCCTGACGACTTTT
TCCGGAACCAACTGTCTCTCGCGCCCGGTCTGGTCTGTTCCGCGCTGCGGAAAGTTCGCGCGCGCCTCAAGAATCCGCTC
AAAAGCGTCGACGAGTATCTCGCGATCCTGACACAGCAGGGGTTGGTCGCCACGGTTGCCGACCTGGAGCAATTCGCCGA
CCTGCTTTGA
ATGAGCCAGTACACGGTCCTGTTCGATGCGAACGTCCTTTATCCCGCGCCGATGCGCGATGCACTGATGCAGTTGGCGGT
CACAGACCTTTTCAAGGCCAAGTGGACGGCCGATATCCATCGGGAGTGGATTGATGCGCTTCTGCGCAATGAACCTCATC
GGGAGCGCGCCGCGCTGGAACGAACTCGCGACTTGATGGACAGGGCCACACGCGACTGTCTGGTCACCGGCTACGAGGCA
TTGGTGCCGGCCCTAACACTGCCGGACCCTGACGATCGGCACGTTCTGGCGGCGGCAATCGTTGGGCGCTGTGACGCGAT
CGTCACGCAGAACCTGAAGGACTTCCCACCAGCGGCACTTGCGCCCTTTGGCATCGAGACCCAACACCCTGACGACTTTT
TCCGGAACCAACTGTCTCTCGCGCCCGGTCTGGTCTGTTCCGCGCTGCGGAAAGTTCGCGCGCGCCTCAAGAATCCGCTC
AAAAGCGTCGACGAGTATCTCGCGATCCTGACACAGCAGGGGTTGGTCGCCACGGTTGCCGACCTGGAGCAATTCGCCGA
CCTGCTTTGA
Antitoxin
Download Length: 155 a.a. Molecular weight: 16891.48 Da Isoelectric Point: 6.4929
>AT30435 WP_007803221.1 NC_023148:c124458-123994 [Phaeobacter gallaeciensis DSM 26640]
MNMLAHRHLPPTPQDAAIARVSGQALSRFAQARAPLKLRVTDSEQMEPIELPAGAVSLLMEILEAMAAGRGVTIIPENAE
LSTVQAAEVLNVSRPFLIKLLEDGAIPHRKVGKHRRVRMEDVMSYKAAIDTEREAALDQLAADAQEQDMGYRSK
MNMLAHRHLPPTPQDAAIARVSGQALSRFAQARAPLKLRVTDSEQMEPIELPAGAVSLLMEILEAMAAGRGVTIIPENAE
LSTVQAAEVLNVSRPFLIKLLEDGAIPHRKVGKHRRVRMEDVMSYKAAIDTEREAALDQLAADAQEQDMGYRSK
Download Length: 465 bp
>AT30435 NC_023148:c124458-123994 [Phaeobacter gallaeciensis DSM 26640]
ATGAACATGCTGGCACACCGACATCTTCCGCCCACGCCGCAGGACGCAGCGATTGCGCGCGTCTCTGGCCAGGCATTGTC
ACGCTTCGCCCAGGCGCGCGCGCCGTTGAAACTTCGTGTGACGGACTCCGAGCAGATGGAGCCGATCGAGCTTCCTGCGG
GCGCCGTATCGCTGCTCATGGAGATCCTCGAGGCGATGGCAGCGGGGCGGGGGGTCACCATCATCCCCGAGAACGCCGAA
CTCTCGACCGTACAGGCCGCTGAGGTTCTGAACGTCTCGCGTCCGTTCCTGATCAAGCTGCTCGAGGATGGTGCCATACC
GCATCGGAAGGTCGGCAAGCATCGCCGCGTCCGCATGGAAGACGTGATGTCCTACAAGGCCGCGATCGATACCGAGCGTG
AAGCTGCGCTCGATCAACTGGCCGCCGACGCTCAAGAGCAGGACATGGGCTACCGCTCGAAATGA
ATGAACATGCTGGCACACCGACATCTTCCGCCCACGCCGCAGGACGCAGCGATTGCGCGCGTCTCTGGCCAGGCATTGTC
ACGCTTCGCCCAGGCGCGCGCGCCGTTGAAACTTCGTGTGACGGACTCCGAGCAGATGGAGCCGATCGAGCTTCCTGCGG
GCGCCGTATCGCTGCTCATGGAGATCCTCGAGGCGATGGCAGCGGGGCGGGGGGTCACCATCATCCCCGAGAACGCCGAA
CTCTCGACCGTACAGGCCGCTGAGGTTCTGAACGTCTCGCGTCCGTTCCTGATCAAGCTGCTCGAGGATGGTGCCATACC
GCATCGGAAGGTCGGCAAGCATCGCCGCGTCCGCATGGAAGACGTGATGTCCTACAAGGCCGCGATCGATACCGAGCGTG
AAGCTGCGCTCGATCAACTGGCCGCCGACGCTCAAGAGCAGGACATGGGCTACCGCTCGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|