Detailed information of TA system TA030429

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3280615..3281498
• Replicon: chromosome
• Accession: NC_023076
• Organism: Pseudomonas monteilii SB3101

Toxin (Protein)

• Gene name: -
• Uniprot ID: V9V4E9
• Locus tag: X970_RS15095
• Protein ID: WP_024087362.1
• Coordinates: 3280615..3281052 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: F8G488
• Locus tag: X970_RS15100
• Protein ID: WP_013973163.1
• Coordinates: 3281049..3281498 (-)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
X970_RS15080	3276985..3278214	-	1230	WP_013973159.1	acyl-CoA dehydrogenase	-
X970_RS15085	3278355..3279281	+	927	WP_013973160.1	LysR family transcriptional regulator	-
X970_RS15090	3279453..3280607	+	1155	WP_024087361.1	aminotransferase class V-fold PLP-dependent enzyme	-
X970_RS15095	3280615..3281052	-	438	WP_024087362.1	RES family NAD+ phosphorylase	Toxin
X970_RS15100	3281049..3281498	-	450	WP_013973163.1	DUF2384 domain-containing protein	Antitoxin
X970_RS15105	3281597..3282250	-	654	WP_013973164.1	oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB	-
X970_RS15110	3282355..3283278	+	924	WP_024087363.1	LysR family transcriptional regulator	-
X970_RS15115	3283326..3284156	+	831	WP_013973166.1	AraC family transcriptional regulator	-
X970_RS15120	3284207..3284791	+	585	WP_013973167.1	LysE family translocator	-
X970_RS15125	3284916..3286130	-	1215	WP_024087364.1	sugar transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-137)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (33-91)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 15996.21 Da
• Isoelectric Point: 5.1199

>T30429 WP_024087362.1 NC_023076:c3281052-3280615 [Pseudomonas monteilii SB3101]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSNQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Nucleotide

• Length: 438 bp

>T30429 NC_023076:c3281052-3280615 [Pseudomonas monteilii SB3101]
GTGATTCTGTGGCGTATCAGCGCCTATGCAGACTTGAGCGGAACGGGCGGCTTGCGCGTCAGCGGCCGCTGGCACCAGGC
GGGCCGGCCAGTGGTGTATGCCGCCACCAGCCCGGCCGGGGCAATGCTGGAGGTGCTTGTGCACCTGGAGATCGACCCTG
AGGATTTCCCCACCACCATGCGGCTGCTGCGTATCGAGTTGCCCGACACCGTTTCGCAAGCGCAGTTGCCCGCCTTGCAG
CCTGGCTGGTCGAACCAGACCGAACTGACCCGGGGCCTGGGCAACCGCTTTCTGGATGAGTGCTCGGCATTGCTGTTGCC
GGTGCCGAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCGCGCCATCCGCAGGCAAACAGCGCCAGGCTCG
AGGTCGAGGACTTCACCCCGGACAGCCGGCTGTTTTAG

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 17004.59 Da
• Isoelectric Point: 6.3405

>AT30429 WP_013973163.1 NC_023076:c3281498-3281049 [Pseudomonas monteilii SB3101]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Nucleotide

• Length: 450 bp

>AT30429 NC_023076:c3281498-3281049 [Pseudomonas monteilii SB3101]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCATGCACTGCTGGAAATCCCCGAACT
CGCCAGTGACTTCGAAATCCACACCCGCATCACCCATGGCTTCGCTGCCACCTGGCTGGTGAAACTGACCGAACTCGGCG
TGTTCACCCCTGTGGAGCGTGACCAGATCATTCCCCTGCGCACGCTGAAAACCCGCATCGAACGTGACCAGCCGCTGACC
GTGGAAGAAAGCGACCGGCTGTTCCGTTCGGCCCATATCACCGCCATGGCCGAAGCCGTGTTCGGCGAGGCAGGCAAGGC
AAAACGCTGGCTGTCCAAGCCCAAGGAGCGCTTCTCGGGGCTGACGCCGATGCAGATGCTAACCACCCAGCAGGGCACCA
CCCAGGTCGAAGAGATGTTGCTGCAGATCGCCGAGGGCTTCGGCCTGTGA

Structures

Toxin

• AlphaFold DB: V9V4E9

Antitoxin

• AlphaFold DB: F8G488