Detailed information of TA system TA030416

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/upstrm_HI1419-dnstrm_HI1420
• Location: 2699320..2699904
• Replicon: chromosome
• Accession: NC_023065
• Organism: Magnetospirillum gryphiswaldense MSR-1 v2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MGMSRV2_RS12760
• Protein ID: WP_024080767.1
• Coordinates: 2699605..2699904 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MGMSRV2_RS12755
• Protein ID: WP_024080766.1
• Coordinates: 2699320..2699601 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MGMSRV2_RS21465	2696513..2696680	-	168	WP_024080760.1	hypothetical protein	-
MGMSRV2_RS12730	2696806..2697051	-	246	WP_024080761.1	hypothetical protein	-
MGMSRV2_RS12735	2697147..2697551	-	405	WP_024080762.1	hypothetical protein	-
MGMSRV2_RS12740	2697548..2698435	-	888	Protein_2486	recombinase zinc beta ribbon domain-containing protein	-
MGMSRV2_RS12745	2698434..2698643	+	210	Protein_2487	hypothetical protein	-
MGMSRV2_RS21470	2698771..2698944	-	174	WP_158497764.1	hypothetical protein	-
MGMSRV2_RS21145	2698979..2699287	+	309	WP_144084306.1	hypothetical protein	-
MGMSRV2_RS12755	2699320..2699601	-	282	WP_024080766.1	putative addiction module antidote protein	Antitoxin
MGMSRV2_RS12760	2699605..2699904	-	300	WP_024080767.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MGMSRV2_RS12765	2699961..2701265	+	1305	WP_024080768.1	AAA family ATPase	-
MGMSRV2_RS12770	2701262..2703769	+	2508	WP_024080769.1	toprim domain-containing protein	-
MGMSRV2_RS12775	2704264..2704731	+	468	WP_024080772.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2697548..2722013	24465

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (4-95)

Antitoxin

• Uncharacterized protein HI1420 (9-90)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 10925.61 Da
• Isoelectric Point: 9.9223

>T30416 WP_024080767.1 NC_023065:c2699904-2699605 [Magnetospirillum gryphiswaldense MSR-1 v2]
MNTLLRTASFDAWLSALADIKGKARILARLTAAESGNFGDCDSVGDGISEMRVHFGPGYRVYFTRRGKVIYLLLLGGDKS
TQTRDIKRAKELAKMIEEA

Nucleotide

• Length: 300 bp

>T30416 NC_023065:c2699904-2699605 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGAACACGCTGCTGCGCACCGCCAGCTTTGATGCATGGCTTTCGGCCTTGGCCGACATCAAGGGAAAGGCCCGCATCCT
GGCCCGGCTGACCGCCGCGGAGTCCGGTAATTTCGGTGACTGTGATTCTGTTGGGGATGGCATCAGCGAGATGCGGGTCC
ATTTCGGGCCGGGATACCGGGTGTACTTCACCCGGCGGGGCAAGGTGATCTATCTGCTGCTGCTGGGCGGCGACAAATCG
ACCCAGACGCGAGACATCAAGCGGGCCAAGGAATTGGCCAAAATGATCGAGGAGGCTTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 9691.05 Da
• Isoelectric Point: 5.0053

>AT30416 WP_024080766.1 NC_023065:c2699601-2699320 [Magnetospirillum gryphiswaldense MSR-1 v2]
MTEQVGAFDIATYLDNGEVVAEYLTAALEDSDPAVFLAALGHVAKARGMSQVAGKAGLGRESLYKAVAPGAHPRYETVRS
LIDALGLKLTISA

Nucleotide

• Length: 282 bp

>AT30416 NC_023065:c2699601-2699320 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGACGGAACAGGTCGGTGCTTTCGACATCGCCACCTATCTCGATAATGGCGAGGTGGTGGCCGAATATCTGACGGCGGC
GCTGGAAGACTCCGATCCGGCGGTCTTTCTGGCCGCGCTCGGCCATGTCGCCAAGGCCCGCGGCATGAGTCAGGTGGCCG
GGAAAGCCGGGCTGGGGCGCGAAAGCCTGTACAAGGCCGTCGCCCCTGGCGCCCATCCGCGTTACGAGACGGTTCGCTCG
CTGATCGACGCGCTGGGGCTGAAGCTGACCATTTCCGCTTGA