Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 2658174..2658699 Replicon chromosome
Accession NC_023065
Organism Magnetospirillum gryphiswaldense MSR-1 v2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MGMSRV2_RS12580 Protein ID WP_024080726.1
Coordinates 2658174..2658455 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag MGMSRV2_RS12585 Protein ID WP_024080727.1
Coordinates 2658442..2658699 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MGMSRV2_RS12560 2653367..2653801 + 435 WP_024080721.1 hypothetical protein -
MGMSRV2_RS12565 2653824..2654783 + 960 WP_024080722.1 hypothetical protein -
MGMSRV2_RS12570 2654795..2655319 + 525 WP_041633608.1 hypothetical protein -
MGMSRV2_RS21460 2655358..2655510 + 153 WP_024080724.1 hypothetical protein -
MGMSRV2_RS12575 2655609..2658170 + 2562 WP_024080725.1 phage tail length tape measure family protein -
MGMSRV2_RS12580 2658174..2658455 - 282 WP_024080726.1 type II toxin-antitoxin system YafQ family toxin Toxin
MGMSRV2_RS12585 2658442..2658699 - 258 WP_024080727.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MGMSRV2_RS12590 2658790..2659284 + 495 WP_024080728.1 hypothetical protein -
MGMSRV2_RS12595 2659292..2660329 + 1038 WP_024080729.1 hypothetical protein -
MGMSRV2_RS12600 2660335..2660652 + 318 WP_024080730.1 hypothetical protein -
MGMSRV2_RS12605 2660823..2663039 + 2217 WP_024080731.1 hypothetical protein -
MGMSRV2_RS12610 2663055..2663327 + 273 WP_144084304.1 hypothetical protein -
MGMSRV2_RS12615 2663331..2663666 + 336 WP_024080733.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2645362..2667551 22189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10948.36 Da        Isoelectric Point: 6.8453

>T30415 WP_024080726.1 NC_023065:c2658455-2658174 [Magnetospirillum gryphiswaldense MSR-1 v2]
MRTINRTGQFKRDYKREKKGRHRETLDADLVDVVSKLVADEPLEERHHDHALTGNWKDHRDCHIKPDLVLIYRLPDEETL
DLVRLGSHSELGL

Download         Length: 282 bp

>T30415 NC_023065:c2658455-2658174 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGCGGACGATTAACCGCACCGGCCAGTTCAAGCGGGACTACAAGCGTGAAAAGAAGGGTCGGCATCGGGAAACCCTCGA
TGCCGACCTTGTCGATGTTGTCTCGAAGCTGGTGGCCGACGAGCCCCTGGAGGAGCGGCATCACGACCATGCCCTGACCG
GGAACTGGAAGGATCATCGCGACTGCCATATCAAGCCCGATCTGGTCCTGATCTACCGACTCCCCGACGAAGAGACGCTC
GATCTGGTGCGTCTCGGCTCGCACAGCGAACTCGGCCTGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9325.82 Da        Isoelectric Point: 4.7824

>AT30415 WP_024080727.1 NC_023065:c2658699-2658442 [Magnetospirillum gryphiswaldense MSR-1 v2]
MNTVVRARIDEHLKDEAALVLSSIGLTVSDAFRMMMVRIATEKRLPFEPLVPNAETIAAMEAARRGDVVRVGSVKDLMAD
LNADD

Download         Length: 258 bp

>AT30415 NC_023065:c2658699-2658442 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGAACACTGTTGTCCGTGCCCGCATCGACGAGCACCTGAAGGACGAGGCAGCACTCGTGCTGTCGTCGATCGGCCTGAC
CGTGTCCGACGCCTTCCGCATGATGATGGTGCGGATCGCCACCGAGAAGCGGTTGCCGTTCGAGCCCCTGGTTCCCAATG
CCGAAACCATCGCCGCGATGGAGGCCGCCCGGCGCGGCGACGTGGTCCGGGTCGGCAGCGTCAAGGATCTGATGGCGGAT
CTGAATGCGGACGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References