Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-Phd |
| Location | 2433299..2433957 | Replicon | chromosome |
| Accession | NC_023065 | ||
| Organism | Magnetospirillum gryphiswaldense MSR-1 v2 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | V6F298 |
| Locus tag | MGMSRV2_RS11405 | Protein ID | WP_024080518.1 |
| Coordinates | 2433299..2433712 (-) | Length | 138 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | V6F4U0 |
| Locus tag | MGMSRV2_RS11410 | Protein ID | WP_024080519.1 |
| Coordinates | 2433709..2433957 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGMSRV2_RS11365 | 2428754..2429104 | - | 351 | WP_024080509.1 | MbcA/ParS/Xre antitoxin family protein | - |
| MGMSRV2_RS11370 | 2429111..2429728 | - | 618 | WP_197538532.1 | LexA family transcriptional regulator | - |
| MGMSRV2_RS11375 | 2429885..2430574 | + | 690 | WP_041633579.1 | hypothetical protein | - |
| MGMSRV2_RS11385 | 2430971..2431279 | + | 309 | WP_024080512.1 | hypothetical protein | - |
| MGMSRV2_RS21690 | 2431597..2431955 | + | 359 | Protein_2216 | hypothetical protein | - |
| MGMSRV2_RS11395 | 2432156..2432566 | + | 411 | WP_024080515.1 | hypothetical protein | - |
| MGMSRV2_RS21075 | 2432571..2432798 | + | 228 | WP_024080516.1 | hypothetical protein | - |
| MGMSRV2_RS11400 | 2432768..2433292 | + | 525 | WP_024080517.1 | DUF1833 domain-containing protein | - |
| MGMSRV2_RS11405 | 2433299..2433712 | - | 414 | WP_024080518.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| MGMSRV2_RS11410 | 2433709..2433957 | - | 249 | WP_024080519.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MGMSRV2_RS11415 | 2433999..2434433 | + | 435 | WP_024080520.1 | C40 family peptidase | - |
| MGMSRV2_RS11420 | 2434433..2436733 | + | 2301 | WP_024080521.1 | hypothetical protein | - |
| MGMSRV2_RS11425 | 2436797..2437234 | + | 438 | WP_024080522.1 | protein P5 | - |
| MGMSRV2_RS11430 | 2437237..2437836 | + | 600 | WP_024080523.1 | hypothetical protein | - |
| MGMSRV2_RS11435 | 2438047..2438427 | - | 381 | WP_144084300.1 | hypothetical protein | - |
| MGMSRV2_RS11440 | 2438378..2438857 | + | 480 | WP_158497756.1 | response regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2426786..2481993 | 55207 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 15137.47 Da Isoelectric Point: 4.7582
>T30413 WP_024080518.1 NC_023065:c2433712-2433299 [Magnetospirillum gryphiswaldense MSR-1 v2]
VSYLVDTCALSELIRPVPAPQVAEWFETVPQEALFISALTLGEIRRGAEKLADGRRRGRIIAWLEIELPDWFESRVLPVD
AAVADEWGRLTARIKQPLPAIDSLIAATALKHRLTVVTRNVADFAAAGVDILNPWEA
VSYLVDTCALSELIRPVPAPQVAEWFETVPQEALFISALTLGEIRRGAEKLADGRRRGRIIAWLEIELPDWFESRVLPVD
AAVADEWGRLTARIKQPLPAIDSLIAATALKHRLTVVTRNVADFAAAGVDILNPWEA
Download Length: 414 bp
>T30413 NC_023065:c2433712-2433299 [Magnetospirillum gryphiswaldense MSR-1 v2]
GTGAGCTATCTGGTCGATACCTGCGCCCTGTCGGAGCTGATCCGGCCCGTCCCGGCGCCACAGGTGGCGGAGTGGTTCGA
GACGGTGCCGCAGGAGGCACTATTCATCAGCGCCCTGACCCTGGGTGAAATCCGCCGGGGTGCCGAGAAACTGGCGGATG
GGCGGCGGCGCGGCCGGATCATCGCCTGGCTGGAGATCGAGTTACCCGACTGGTTCGAGAGCCGCGTGCTGCCGGTCGAT
GCCGCTGTCGCCGACGAATGGGGCCGCCTGACCGCACGGATCAAACAACCGCTGCCAGCCATCGACAGCCTGATCGCCGC
CACCGCCCTGAAGCACCGGCTCACCGTGGTAACCCGCAACGTCGCCGACTTCGCGGCGGCCGGCGTCGATATCCTCAATC
CCTGGGAGGCATAG
GTGAGCTATCTGGTCGATACCTGCGCCCTGTCGGAGCTGATCCGGCCCGTCCCGGCGCCACAGGTGGCGGAGTGGTTCGA
GACGGTGCCGCAGGAGGCACTATTCATCAGCGCCCTGACCCTGGGTGAAATCCGCCGGGGTGCCGAGAAACTGGCGGATG
GGCGGCGGCGCGGCCGGATCATCGCCTGGCTGGAGATCGAGTTACCCGACTGGTTCGAGAGCCGCGTGCTGCCGGTCGAT
GCCGCTGTCGCCGACGAATGGGGCCGCCTGACCGCACGGATCAAACAACCGCTGCCAGCCATCGACAGCCTGATCGCCGC
CACCGCCCTGAAGCACCGGCTCACCGTGGTAACCCGCAACGTCGCCGACTTCGCGGCGGCCGGCGTCGATATCCTCAATC
CCTGGGAGGCATAG
Antitoxin
Download Length: 83 a.a. Molecular weight: 9225.43 Da Isoelectric Point: 8.7082
>AT30413 WP_024080519.1 NC_023065:c2433957-2433709 [Magnetospirillum gryphiswaldense MSR-1 v2]
MHAWQVQDAKARFSELLRSAAAEGPQAITVRGRTTAVVMSQDEYERLKGRKPSLVEFLRSSPLSGVDLDIERDRSPSRNI
EL
MHAWQVQDAKARFSELLRSAAAEGPQAITVRGRTTAVVMSQDEYERLKGRKPSLVEFLRSSPLSGVDLDIERDRSPSRNI
EL
Download Length: 249 bp
>AT30413 NC_023065:c2433957-2433709 [Magnetospirillum gryphiswaldense MSR-1 v2]
ATGCACGCGTGGCAGGTTCAGGACGCCAAGGCCCGGTTCAGCGAGCTGCTGCGCAGCGCCGCAGCCGAAGGCCCGCAGGC
GATCACCGTTCGCGGCCGCACCACGGCGGTGGTGATGTCCCAGGACGAGTACGAACGGCTGAAGGGGCGCAAGCCGTCGC
TGGTGGAATTCCTGCGGTCGTCGCCGCTGTCCGGCGTGGACCTCGATATCGAGCGCGACCGCTCGCCGTCGCGGAACATC
GAGTTGTGA
ATGCACGCGTGGCAGGTTCAGGACGCCAAGGCCCGGTTCAGCGAGCTGCTGCGCAGCGCCGCAGCCGAAGGCCCGCAGGC
GATCACCGTTCGCGGCCGCACCACGGCGGTGGTGATGTCCCAGGACGAGTACGAACGGCTGAAGGGGCGCAAGCCGTCGC
TGGTGGAATTCCTGCGGTCGTCGCCGCTGTCCGGCGTGGACCTCGATATCGAGCGCGACCGCTCGCCGTCGCGGAACATC
GAGTTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|