Detailed information of TA system TA030395

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 1815363..1815870
• Replicon: chromosome
• Accession: NC_023035
• Organism: Salinispira pacifica

Toxin (Protein)

• Gene name: relB
• Uniprot ID: V5WIV5
• Locus tag: L21SP2_RS08020
• Protein ID: WP_024268005.1
• Coordinates: 1815363..1815623 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: L21SP2_RS08025
• Protein ID: WP_041401366.1
• Coordinates: 1815616..1815870 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L21SP2_RS07995	1811839..1812690	+	852	WP_024268001.1	ABC transporter ATP-binding protein	-
L21SP2_RS08000	1812700..1813062	+	363	WP_041401360.1	hypothetical protein	-
L21SP2_RS08005	1813062..1813769	+	708	WP_041401363.1	hypothetical protein	-
L21SP2_RS08010	1813771..1814826	+	1056	WP_024268003.1	ABC transporter permease	-
L21SP2_RS08015	1814896..1815099	+	204	WP_024268004.1	hypothetical protein	-
L21SP2_RS08020	1815363..1815623	-	261	WP_024268005.1	Txe/YoeB family addiction module toxin	Toxin
L21SP2_RS08025	1815616..1815870	-	255	WP_041401366.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
L21SP2_RS08035	1816409..1817068	-	660	WP_024268007.1	PrsW family intramembrane metalloprotease	-
L21SP2_RS08040	1817071..1818120	-	1050	WP_024268008.1	histidinol-phosphate transaminase	-
L21SP2_RS18030	1818163..1818912	+	750	WP_211233437.1	YgjV family protein	-
L21SP2_RS08050	1818982..1819224	-	243	WP_024268010.1	DUF3783 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (7-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10247.38 Da
• Isoelectric Point: 7.2737

>T30395 WP_024268005.1 NC_023035:c1815623-1815363 [Salinispira pacifica]
MSRGVNWHESAWEDYEYWQSQDRKTLKKINNLIKAARRTPEEGAESLKGDLSGYFSRHINKKDVLVYTYDDDSITIIQCR
FHYSDK

Nucleotide

• Length: 261 bp

>T30395 NC_023035:c1815623-1815363 [Salinispira pacifica]
ATGAGTAGAGGGGTCAACTGGCATGAGTCGGCATGGGAGGATTATGAGTACTGGCAAAGTCAAGACCGCAAAACACTTAA
GAAGATTAATAATTTAATAAAGGCAGCACGACGAACGCCGGAAGAAGGAGCCGAATCATTAAAGGGAGACCTTTCAGGTT
ACTTCTCCCGGCATATCAACAAGAAAGATGTATTGGTTTACACCTACGATGATGATTCAATCACCATCATTCAATGCCGA
TTCCATTATTCTGATAAGTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9449.63 Da
• Isoelectric Point: 5.0628

>AT30395 WP_041401366.1 NC_023035:c1815870-1815616 [Salinispira pacifica]
MRITTYTDARNNLRQLINDVVDTSTETVITSKEGRDVVVMSLADYNGWTTTNHLLSTPENASRLLKAVEDVKAGRVIKRD
LLDE

Nucleotide

• Length: 255 bp

>AT30395 NC_023035:c1815870-1815616 [Salinispira pacifica]
ATGAGAATTACAACCTATACTGATGCGCGGAACAATCTCAGGCAATTGATTAATGACGTTGTAGATACCTCTACAGAAAC
TGTCATCACCTCAAAGGAAGGCCGGGATGTAGTGGTGATGTCCCTTGCAGATTACAATGGCTGGACAACCACCAACCACC
TGCTTAGTACACCTGAGAACGCTAGCCGCCTGTTAAAGGCCGTTGAAGATGTTAAGGCCGGGAGAGTTATCAAGCGAGAT
CTATTAGATGAGTAG

Structures

Toxin

• AlphaFold DB: V5WIV5