Detailed information of TA system TA030379

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 455118..455771
• Replicon: chromosome
• Accession: NC_023028
• Organism: Acinetobacter baumannii ZW85-1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: P795_RS02195
• Protein ID: WP_023896177.1
• Coordinates: 455382..455771 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: P795_RS02190
• Protein ID: WP_001288210.1
• Coordinates: 455118..455375 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P795_RS02170	450634..451641	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
P795_RS02175	451660..452037	+	378	WP_001216380.1	50S ribosomal protein L17	-
P795_RS02180	452219..453709	+	1491	WP_000415133.1	NAD(P)/FAD-dependent oxidoreductase	-
P795_RS02185	453758..454930	-	1173	WP_001190547.1	acyl-CoA dehydrogenase family protein	-
P795_RS02190	455118..455375	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
P795_RS02195	455382..455771	+	390	WP_023896177.1	hypothetical protein	Toxin
P795_RS02200	456540..457625	+	1086	WP_000049106.1	hypothetical protein	-
P795_RS02205	457703..458269	+	567	WP_000651536.1	rhombosortase	-
P795_RS02210	458457..460652	+	2196	WP_001158905.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15642.90 Da
• Isoelectric Point: 10.3889

>T30379 WP_023896177.1 NC_023028:455382-455771 [Acinetobacter baumannii ZW85-1]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLTQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T30379 NC_023028:455382-455771 [Acinetobacter baumannii ZW85-1]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTACACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT30379 WP_001288210.1 NC_023028:455118-455375 [Acinetobacter baumannii ZW85-1]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT30379 NC_023028:455118-455375 [Acinetobacter baumannii ZW85-1]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7