Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ(toxin) |
Location | 774424..775048 | Replicon | chromosome |
Accession | NC_022911 | ||
Organism | Helicobacter pylori BM012S |
Toxin (Protein)
Gene name | relE | Uniprot ID | V5NM94 |
Locus tag | U064_RS03930 | Protein ID | WP_023592055.1 |
Coordinates | 774782..775048 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | V5NMW4 |
Locus tag | U064_RS03925 | Protein ID | WP_023592054.1 |
Coordinates | 774424..774801 (+) | Length | 126 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
U064_RS03895 | 769559..769795 | + | 237 | WP_000335461.1 | HypC/HybG/HupF family hydrogenase formation chaperone | - |
U064_RS03900 | 769813..770925 | + | 1113 | WP_023592052.1 | hydrogenase formation protein HypD | - |
U064_RS08430 | 770892..771163 | + | 272 | Protein_727 | hypothetical protein | - |
U064_RS03920 | 771984..774214 | + | 2231 | Protein_728 | Hop family adhesin BabA | - |
U064_RS03925 | 774424..774801 | + | 378 | WP_023592054.1 | hypothetical protein | Antitoxin |
U064_RS03930 | 774782..775048 | + | 267 | WP_023592055.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
U064_RS03935 | 775154..775678 | - | 525 | WP_001135637.1 | acyl-CoA thioesterase | - |
U064_RS03940 | 775818..776672 | + | 855 | WP_023592056.1 | SDR family oxidoreductase | - |
U064_RS03945 | 776665..777645 | + | 981 | WP_000921458.1 | iron ABC transporter permease | - |
U064_RS03950 | 777645..778412 | + | 768 | WP_023592057.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10332.17 Da Isoelectric Point: 8.0602
>T30354 WP_023592055.1 NC_022911:774782-775048 [Helicobacter pylori BM012S]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILTLRKKEPLDPQFKDHALKGKWKPFRECHIKADILLVYLVENDELILLR
LGSHSELF
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILTLRKKEPLDPQFKDHALKGKWKPFRECHIKADILLVYLVENDELILLR
LGSHSELF
Download Length: 267 bp
>T30354 NC_022911:774782-775048 [Helicobacter pylori BM012S]
GTGTTAAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCGCTAGATCCCCAATTTAAAGATCATGCTTTGAAAGGAAAGTGGA
AACCTTTTAGGGAATGCCATATTAAAGCTGATATTTTGCTTGTGTATTTAGTGGAAAATGATGAGCTGATTTTGTTAAGG
TTAGGCAGTCATAGCGAGTTGTTTTGA
GTGTTAAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCGCTAGATCCCCAATTTAAAGATCATGCTTTGAAAGGAAAGTGGA
AACCTTTTAGGGAATGCCATATTAAAGCTGATATTTTGCTTGTGTATTTAGTGGAAAATGATGAGCTGATTTTGTTAAGG
TTAGGCAGTCATAGCGAGTTGTTTTGA
Antitoxin
Download Length: 126 a.a. Molecular weight: 14715.70 Da Isoelectric Point: 8.9992
>AT30354 WP_023592054.1 NC_022911:774424-774801 [Helicobacter pylori BM012S]
MPNSSTKKDYTKYSEKQLVNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCF
GHETPNIQTQQAMRDALNKETDLIVEDFSSYSDERKKALGVKTQP
MPNSSTKKDYTKYSEKQLVNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCF
GHETPNIQTQQAMRDALNKETDLIVEDFSSYSDERKKALGVKTQP
Download Length: 378 bp
>AT30354 NC_022911:774424-774801 [Helicobacter pylori BM012S]
ATGCCTAATTCTTCCACCAAAAAAGACTACACAAAATACAGCGAAAAACAGCTTGTTAACTTAATCCATCAATTAGAGCG
AAAAATTAAAAAGATGCAAAATGATAGAGTTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTT
GGGCATGAAACCCCAAACATTCAAACGCAACAAGCCATGAGAGACGCGCTCAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTACAGCGATGAAAGAAAAAAGGCGTTAGGTGTTAAAACTCAACCTTAA
ATGCCTAATTCTTCCACCAAAAAAGACTACACAAAATACAGCGAAAAACAGCTTGTTAACTTAATCCATCAATTAGAGCG
AAAAATTAAAAAGATGCAAAATGATAGAGTTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTT
GGGCATGAAACCCCAAACATTCAAACGCAACAAGCCATGAGAGACGCGCTCAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTACAGCGATGAAAGAAAAAAGGCGTTAGGTGTTAAAACTCAACCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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