Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3526556..3527170 Replicon chromosome
Accession NC_022904
Organism Pandoraea pnomenusa 3kgm

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag U875_RS15930 Protein ID WP_031627339.1
Coordinates 3526556..3526852 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag U875_RS15935 Protein ID WP_023596882.1
Coordinates 3526856..3527170 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
U875_RS25195 3522863..3523561 + 699 WP_144347374.1 DUF4145 domain-containing protein -
U875_RS15915 3523573..3524469 - 897 WP_023596879.1 hypothetical protein -
U875_RS15920 3524717..3525478 - 762 Protein_3118 hypothetical protein -
U875_RS15925 3525532..3526059 - 528 WP_023596881.1 hypothetical protein -
U875_RS15930 3526556..3526852 + 297 WP_031627339.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
U875_RS15935 3526856..3527170 + 315 WP_023596882.1 putative addiction module antidote protein Antitoxin
U875_RS15940 3527180..3527971 - 792 WP_023596883.1 DNA adenine methylase -
U875_RS25630 3528298..3528684 - 387 WP_144347376.1 hypothetical protein -
U875_RS15950 3528669..3529133 - 465 WP_023596885.1 lysozyme -
U875_RS25635 3529137..3529322 - 186 WP_144347378.1 hypothetical protein -
U875_RS15955 3529536..3529853 + 318 WP_031627340.1 tyrosine-type recombinase/integrase -
U875_RS15965 3530041..3531954 - 1914 WP_023596888.1 selenocysteine-specific translation elongation factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-94)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10734.47 Da        Isoelectric Point: 10.1723

>T30349 WP_031627339.1 NC_022904:3526556-3526852 [Pandoraea pnomenusa 3kgm]
MTKILQHPEFSKWFSGLRDRKGVAAIAQRLDRLALGNPGNVKPVGEGVSELKIDVGPGYRVYFVQRGAVLVVLLCGGDKS
TQAKDIKRAKKLADELED

Download         Length: 297 bp

>T30349 NC_022904:3526556-3526852 [Pandoraea pnomenusa 3kgm]
ATGACGAAAATTCTCCAGCACCCCGAGTTCAGCAAATGGTTTTCCGGCCTGCGTGATCGCAAGGGCGTCGCAGCCATCGC
TCAACGGCTCGACCGCCTGGCGCTCGGAAATCCCGGCAACGTAAAGCCGGTCGGCGAGGGTGTTTCGGAATTGAAGATCG
ACGTCGGCCCAGGCTATCGCGTCTACTTTGTTCAACGCGGGGCCGTGCTGGTTGTCCTGCTGTGCGGTGGCGACAAGTCG
ACGCAAGCCAAGGACATCAAGCGCGCGAAGAAGCTGGCCGACGAACTGGAGGACTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11119.59 Da        Isoelectric Point: 4.8782

>AT30349 WP_023596882.1 NC_022904:3526856-3527170 [Pandoraea pnomenusa 3kgm]
MKLSELKEFDAAEALKDDETIKHYLSLAFEGGDSREIQRALGTVARARGMSALARESGIAREALYRALSDTGNPEFATIM
KVLGALGLHLTLAPNSESPDAVTA

Download         Length: 315 bp

>AT30349 NC_022904:3526856-3527170 [Pandoraea pnomenusa 3kgm]
ATGAAACTAAGCGAACTGAAGGAATTTGACGCCGCAGAGGCGCTGAAGGACGACGAGACGATCAAGCACTACCTTTCGCT
CGCGTTTGAAGGTGGGGATTCTCGCGAAATTCAACGGGCGCTCGGCACCGTCGCCCGCGCTCGCGGGATGAGCGCCCTTG
CCCGCGAGTCTGGCATCGCTCGCGAAGCACTGTATCGCGCTCTGTCCGACACGGGCAATCCGGAATTCGCAACCATCATG
AAGGTACTGGGCGCACTTGGCCTGCACCTCACCTTGGCCCCGAACTCCGAATCGCCCGATGCCGTCACGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References