Detailed information of TA system TA030163

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 4927602..4928139
• Replicon: chromosome
• Accession: NC_022541
• Organism: Xanthomonas citri pv. fuscans

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9YU06
• Locus tag: XFF4834R_RS20730
• Protein ID: WP_017158383.1
• Coordinates: 4927858..4928139 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: XFF4834R_RS20725
• Protein ID: WP_017158384.1
• Coordinates: 4927602..4927871 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XFF4834R_RS20690	4922863..4923471	+	609	WP_017154888.1	hypothetical protein	-
XFF4834R_RS20695	4923584..4924216	+	633	WP_007966093.1	ParA family protein	-
XFF4834R_RS20700	4924209..4924541	+	333	WP_007966095.1	hypothetical protein	-
XFF4834R_RS20705	4924608..4924892	+	285	WP_017154887.1	hypothetical protein	-
XFF4834R_RS20710	4924899..4926086	+	1188	WP_022560475.1	zeta toxin family protein	-
XFF4834R_RS20720	4926531..4927493	+	963	WP_022560476.1	recombinase family protein	-
XFF4834R_RS20725	4927602..4927871	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
XFF4834R_RS20730	4927858..4928139	+	282	WP_017158383.1	type II toxin-antitoxin system YafQ family toxin	Toxin
XFF4834R_RS20735	4928277..4928630	-	354	WP_033481414.1	hypothetical protein	-
XFF4834R_RS20740	4928676..4929383	-	708	WP_022560478.1	hypothetical protein	-
XFF4834R_RS20745	4929380..4929826	-	447	WP_033481413.1	hypothetical protein	-
XFF4834R_RS20750	4930172..4930567	+	396	WP_022560480.1	hypothetical protein	-
XFF4834R_RS20755	4930665..4930934	+	270	WP_033481412.1	hypothetical protein	-
XFF4834R_RS20760	4930931..4931224	+	294	WP_011345592.1	type II toxin-antitoxin system RelE/ParE family toxin	-
XFF4834R_RS20765	4931337..4931957	+	621	WP_011345593.1	hypothetical protein	-
XFF4834R_RS24395	4932156..4932497	+	342	WP_029561219.1	hypothetical protein	-
XFF4834R_RS20775	4932569..4932766	+	198	WP_022560481.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4923584..4952770	29186

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10679.06 Da
• Isoelectric Point: 8.9188

>T30163 WP_017158383.1 NC_022541:4927858-4928139 [Xanthomonas citri pv. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Nucleotide

• Length: 282 bp

>T30163 NC_022541:4927858-4928139 [Xanthomonas citri pv. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT30163 WP_017158384.1 NC_022541:4927602-4927871 [Xanthomonas citri pv. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT30163 NC_022541:4927602-4927871 [Xanthomonas citri pv. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Toxin

• AlphaFold DB: A0A7X9YU06

Antitoxin

• AlphaFold DB: A0A7X9UWY6