30162

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4466909..4467270 Replicon chromosome
Accession NC_022541
Organism Xanthomonas citri pv. fuscans

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XFF4834R_RS18920 Protein ID WP_005914328.1
Coordinates 4466909..4467043 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XFF4834R_RS18925 Protein ID WP_003486606.1
Coordinates 4467118..4467270 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFF4834R_RS18905 4463938..4464981 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
XFF4834R_RS18910 4465011..4466300 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
XFF4834R_RS18915 4466473..4466682 - 210 WP_016904514.1 CsbD family protein -
XFF4834R_RS18920 4466909..4467043 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XFF4834R_RS18925 4467118..4467270 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XFF4834R_RS18930 4467377..4468300 - 924 WP_007966941.1 arginase -
XFF4834R_RS18935 4468621..4469073 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XFF4834R_RS18940 4469137..4469496 + 360 WP_003486613.1 hypothetical protein -
XFF4834R_RS18945 4469593..4470507 + 915 WP_022560229.1 hypothetical protein -
XFF4834R_RS18950 4470504..4471046 + 543 WP_003486615.1 GTPase -
XFF4834R_RS18955 4471526..4472209 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T30162 WP_005914328.1 NC_022541:c4467043-4466909 [Xanthomonas citri pv. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T30162 NC_022541:c4467043-4466909 [Xanthomonas citri pv. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT30162 WP_003486606.1 NC_022541:c4467270-4467118 [Xanthomonas citri pv. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT30162 NC_022541:c4467270-4467118 [Xanthomonas citri pv. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References