Detailed information of TA system TA030115

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): CapRel-ATcapRel/-
• Location: 2445940..2446910
• Replicon: chromosome
• Accession: NC_022438
• Organism: Leifsonia xyli subsp. cynodontis DSM 46306

Toxin (Protein)

• Gene name: capRel
• Uniprot ID: U3P9M1
• Locus tag: O159_RS11740
• Protein ID: WP_021755999.1
• Coordinates: 2446209..2446910 (-)
• Length: 234 a.a.

Antitoxin (Protein)

• Gene name: ATcapRel
• Uniprot ID: -
• Locus tag: O159_RS11735
• Protein ID: WP_043993737.1
• Coordinates: 2445940..2446209 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
O159_RS11725	2442555..2443082	+	528	WP_043993763.1	SRPBCC domain-containing protein	-
O159_RS11730	2443535..2443870	+	336	WP_021754404.1	hypothetical protein	-
O159_RS14720	2444902..2445435	-	534	WP_169725679.1	hypothetical protein	-
O159_RS11735	2445940..2446209	-	270	WP_043993737.1	hypothetical protein	Antitoxin
O159_RS11740	2446209..2446910	-	702	WP_021755999.1	RelA/SpoT domain-containing protein	Toxin
O159_RS11745	2447019..2447366	-	348	WP_021754741.1	hypothetical protein	-
O159_RS11750	2447363..2447701	-	339	WP_021756000.1	DUF2746 domain-containing protein	-
O159_RS13495	2447709..2448572	-	864	Protein_2394	glycoside hydrolase family 25 protein	-
O159_RS11765	2448908..2450104	-	1197	WP_021754744.1	hypothetical protein	-
O159_RS11770	2450109..2451281	-	1173	WP_021754745.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2443535..2459291	15756

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RelA/SpoT (68-167)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 234 a.a.
• Molecular weight: 26227.40 Da
• Isoelectric Point: 9.8522

>T30115 WP_021755999.1 NC_022438:c2446910-2446209 [Leifsonia xyli subsp. cynodontis DSM 46306]
VDEIVISKSQVDKAGSVIRKCFRGELGDEAQVKHAFRVVEAFRAAHQVPLAKANMGLRSMIKTEGCQVEVSQRLKRFTTI
IDKLTAREQTLALSGMQDIGGCRAILGSVEEIRRVEARLRKRRPVTRYKDYITDPRLSGYRGVHLVVKYDQRCVEIQLRT
PLMHLWAITVERQSALVGENLKQDGSHAVQQLMSVMSRAMAIDEAGETIPSSLLEEIERLRVQATPYLEKGSV

Nucleotide

• Length: 702 bp

>T30115 NC_022438:c2446910-2446209 [Leifsonia xyli subsp. cynodontis DSM 46306]
GTGGATGAGATCGTGATCTCGAAATCGCAGGTTGACAAGGCCGGCTCAGTGATTCGTAAGTGCTTCCGCGGCGAACTCGG
TGATGAAGCACAGGTGAAGCACGCATTCCGTGTGGTTGAGGCGTTCCGGGCCGCTCATCAGGTCCCACTCGCCAAGGCCA
ACATGGGTCTGCGGTCGATGATCAAGACCGAAGGTTGTCAGGTTGAAGTCTCGCAGCGTCTCAAGCGATTCACGACGATC
ATCGACAAACTCACCGCCCGGGAGCAGACGCTTGCGCTCTCAGGGATGCAAGACATTGGCGGTTGCCGCGCCATCCTCGG
CAGCGTCGAGGAGATCCGCCGTGTCGAGGCCCGGCTACGCAAGCGCCGTCCCGTGACCAGATACAAGGATTACATCACTG
ACCCTCGCCTTTCAGGCTATCGCGGAGTGCATCTGGTTGTTAAGTATGATCAACGGTGTGTGGAGATCCAGCTACGCACC
CCGCTCATGCATCTTTGGGCGATCACGGTCGAGCGCCAGTCGGCGCTCGTCGGTGAGAACCTCAAACAAGACGGATCTCA
TGCCGTCCAACAGTTGATGTCGGTGATGTCACGGGCAATGGCCATCGACGAGGCAGGCGAGACCATACCCAGCTCTTTAC
TCGAAGAGATCGAACGCCTTAGAGTTCAAGCAACTCCCTACCTCGAGAAAGGATCGGTGTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10029.03 Da
• Isoelectric Point: 4.4180

>AT30115 WP_043993737.1 NC_022438:c2446209-2445940 [Leifsonia xyli subsp. cynodontis DSM 46306]
MTTIQHFILVFDHSKGHLTGEPLEYGQDSESALARYSELEEEFRSNTNMDIVLIGSDSLDTVKVTHANYFDGTAAFAKYL
NDIQAQRTN

Nucleotide

• Length: 270 bp

>AT30115 NC_022438:c2446209-2445940 [Leifsonia xyli subsp. cynodontis DSM 46306]
ATGACGACTATCCAGCATTTCATTCTGGTGTTCGACCACTCCAAAGGTCACCTCACCGGCGAACCGCTCGAATACGGTCA
GGACAGCGAGAGCGCCCTTGCCCGCTACTCCGAGCTTGAGGAAGAGTTCCGCAGCAACACGAACATGGACATCGTCCTCA
TCGGCTCGGACTCTCTCGATACCGTCAAGGTCACCCACGCCAACTACTTCGATGGGACCGCTGCGTTCGCGAAGTACCTG
AACGACATTCAGGCACAACGAACCAACTAA

Structures

Toxin

• AlphaFold DB: U3P9M1