Detailed information of TA system TA030114

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): CapRel-ATcapRel/-
• Location: 2345036..2345913
• Replicon: chromosome
• Accession: NC_022438
• Organism: Leifsonia xyli subsp. cynodontis DSM 46306

Toxin (Protein)

• Gene name: capRel
• Uniprot ID: -
• Locus tag: O159_RS11260
• Protein ID: WP_021755911.1
• Coordinates: 2345036..2345644 (+)
• Length: 203 a.a.

Antitoxin (Protein)

• Gene name: ATcapRel
• Uniprot ID: -
• Locus tag: O159_RS11265
• Protein ID: WP_043993737.1
• Coordinates: 2345644..2345913 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
O159_RS11240	2341127..2341651	+	525	WP_021755908.1	IS481 family transposase	-
O159_RS11245	2341838..2343328	+	1491	WP_043993733.1	polygalacturonase	-
O159_RS15100	2343595..2343759	+	165	WP_169725668.1	hypothetical protein	-
O159_RS11250	2343870..2344262	+	393	WP_043993735.1	hypothetical protein	-
O159_RS13445	2344330..2344605	+	276	WP_169725697.1	hypothetical protein	-
O159_RS15105	2344714..2344980	+	267	WP_052323540.1	hypothetical protein	-
O159_RS11260	2345036..2345644	+	609	WP_021755911.1	RelA/SpoT domain-containing protein	Toxin
O159_RS11265	2345644..2345913	+	270	WP_043993737.1	hypothetical protein	Antitoxin
O159_RS11270	2346520..2347242	-	723	WP_043993977.1	hypothetical protein	-
O159_RS11275	2347939..2348193	-	255	WP_021755913.1	hypothetical protein	-
O159_RS11280	2349009..2349596	-	588	WP_144267677.1	hypothetical protein	-
O159_RS11285	2349593..2349910	-	318	WP_021755915.1	helix-turn-helix domain-containing protein	-
O159_RS14230	2350063..2350852	-	790	Protein_2293	IS5 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2324338..2368594	44256
	-	flank	IS/Tn	-	-	2340977..2341090	113

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RelA/SpoT (41-139)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 203 a.a.
• Molecular weight: 22867.60 Da
• Isoelectric Point: 10.2225

>T30114 WP_021755911.1 NC_022438:2345036-2345644 [Leifsonia xyli subsp. cynodontis DSM 46306]
VKHAFRVVEAFRAAHQVPLAKANMGLRSMIKTEGCQVEVSQRLKRFTTIIDKLTAREQTLALSGMQDIGGCRAILGSVEE
IRRVEARLRKRRPVTRYKDYITDPRLSGYRGVHLVVKYDQRCVEIQLRTPLMHLWAITVERQSALVGENLKQDGSHAVQQ
LMSVMSRAMAIDEAGETIPSSLLEEIERLRVQATPYLEKGSV

Nucleotide

• Length: 609 bp

>T30114 NC_022438:2345036-2345644 [Leifsonia xyli subsp. cynodontis DSM 46306]
GTGAAGCACGCATTCCGTGTGGTTGAGGCGTTCCGGGCCGCTCATCAGGTCCCACTCGCCAAGGCCAACATGGGTCTGCG
GTCGATGATCAAGACCGAAGGTTGTCAGGTTGAAGTCTCGCAGCGTCTCAAGCGATTCACGACGATCATCGACAAACTCA
CCGCCCGGGAGCAGACGCTTGCGCTCTCAGGGATGCAAGACATTGGCGGTTGCCGCGCCATCCTCGGCAGCGTCGAGGAG
ATCCGCCGTGTCGAGGCCCGGCTACGCAAGCGCCGTCCCGTGACCAGATACAAGGATTACATCACTGACCCTCGCCTTTC
AGGCTATCGCGGAGTGCATCTGGTTGTTAAGTATGATCAACGGTGTGTGGAGATCCAGCTACGCACCCCGCTCATGCATC
TTTGGGCGATCACGGTCGAGCGCCAGTCGGCGCTCGTCGGTGAGAACCTCAAACAAGACGGATCTCATGCCGTCCAACAG
TTGATGTCGGTGATGTCACGGGCAATGGCCATCGACGAGGCAGGCGAGACCATACCCAGCTCTTTACTCGAAGAGATCGA
ACGCCTTAGAGTTCAAGCAACTCCCTACCTCGAGAAAGGATCGGTGTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10029.03 Da
• Isoelectric Point: 4.4180

>AT30114 WP_043993737.1 NC_022438:2345644-2345913 [Leifsonia xyli subsp. cynodontis DSM 46306]
MTTIQHFILVFDHSKGHLTGEPLEYGQDSESALARYSELEEEFRSNTNMDIVLIGSDSLDTVKVTHANYFDGTAAFAKYL
NDIQAQRTN

Nucleotide

• Length: 270 bp

>AT30114 NC_022438:2345644-2345913 [Leifsonia xyli subsp. cynodontis DSM 46306]
ATGACGACTATCCAGCATTTCATTCTGGTGTTCGACCACTCCAAAGGTCACCTCACCGGCGAACCGCTCGAATACGGTCA
GGACAGCGAGAGCGCCCTTGCCCGCTACTCCGAGCTTGAGGAAGAGTTCCGCAGCAACACGAACATGGACATCGTCCTCA
TCGGCTCGGACTCTCTCGATACCGTCAAGGTCACCCACGCCAACTACTTCGATGGGACCGCTGCGTTCGCGAAGTACCTG
AACGACATTCAGGCACAACGAACCAACTAA