Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 949243..950204 | Replicon | chromosome |
| Accession | NC_022224 | ||
| Organism | Listonella anguillarum M3 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | F7YRB7 |
| Locus tag | N175_RS18070 | Protein ID | WP_013868567.1 |
| Coordinates | 949243..949776 (-) | Length | 178 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | N175_RS19635 | Protein ID | WP_013868568.1 |
| Coordinates | 949773..950204 (-) | Length | 144 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N175_RS19100 | 944669..944842 | - | 174 | Protein_815 | pentapeptide repeat-containing protein | - |
| N175_RS18050 | 945737..946393 | - | 657 | WP_013868559.1 | hypothetical protein | - |
| N175_RS19110 | 946433..946549 | - | 117 | WP_080749045.1 | DUF3265 domain-containing protein | - |
| N175_RS18055 | 946546..946890 | - | 345 | WP_013868560.1 | hypothetical protein | - |
| N175_RS18060 | 947041..947589 | - | 549 | WP_019281391.1 | hypothetical protein | - |
| N175_RS19115 | 947643..947768 | - | 126 | WP_013868562.1 | DUF3265 domain-containing protein | - |
| N175_RS18065 | 948276..948557 | - | 282 | WP_029190024.1 | hypothetical protein | - |
| N175_RS18070 | 949243..949776 | - | 534 | WP_013868567.1 | GNAT family N-acetyltransferase | Toxin |
| N175_RS19635 | 949773..950204 | - | 432 | WP_013868568.1 | DUF1778 domain-containing protein | Antitoxin |
| N175_RS18080 | 950723..951238 | - | 516 | WP_013868571.1 | GNAT family N-acetyltransferase | - |
| N175_RS19130 | 951276..951368 | - | 93 | WP_072600976.1 | DUF3265 domain-containing protein | - |
| N175_RS19460 | 951483..951566 | + | 84 | Protein_826 | helix-turn-helix domain-containing protein | - |
| N175_RS18085 | 951597..952031 | + | 435 | WP_011154684.1 | recombination regulator RecX | - |
| N175_RS19135 | 952322..952414 | + | 93 | WP_193386251.1 | DUF3265 domain-containing protein | - |
| N175_RS18095 | 953176..953418 | - | 243 | WP_019281433.1 | hypothetical protein | - |
| N175_RS18645 | 953405..953854 | - | 450 | WP_013868575.1 | hypothetical protein | - |
| N175_RS18110 | 954271..954780 | + | 510 | WP_013868576.1 | ATPase AAA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 934165..944842 | 10677 | |
| - | inside | Integron | - | - | 945053..951388 | 6335 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 178 a.a. Molecular weight: 20222.47 Da Isoelectric Point: 9.1188
>T29967 WP_013868567.1 NC_022224:c949776-949243 [Vibrio anguillarum M3]
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
Download Length: 534 bp
>T29967 NC_022224:c949776-949243 [Vibrio anguillarum M3]
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
Antitoxin
Download Length: 144 a.a. Molecular weight: 15859.40 Da Isoelectric Point: 7.0831
>AT29967 WP_013868568.1 NC_022224:c950204-949773 [Vibrio anguillarum M3]
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
Download Length: 432 bp
>AT29967 NC_022224:c950204-949773 [Vibrio anguillarum M3]
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|