Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-VagC |
| Location | 150849..151528 | Replicon | plasmid Apa386Bp1 |
| Accession | NC_021976 | ||
| Organism | Acetobacter pasteurianus 386B | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A2G4REI9 |
| Locus tag | APA386B_RS13775 | Protein ID | WP_035362716.1 |
| Coordinates | 150849..151259 (-) | Length | 137 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | APA386B_RS13780 | Protein ID | WP_003626741.1 |
| Coordinates | 151256..151528 (-) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| APA386B_RS13745 | 146833..147681 | + | 849 | WP_035362718.1 | hypothetical protein | - |
| APA386B_RS13750 | 147684..148148 | + | 465 | WP_020936768.1 | hypothetical protein | - |
| APA386B_RS13755 | 148245..149048 | + | 804 | WP_003626746.1 | hypothetical protein | - |
| APA386B_RS13760 | 149060..149461 | + | 402 | WP_020936770.1 | hypothetical protein | - |
| APA386B_RS13765 | 150051..150251 | - | 201 | WP_006560470.1 | hypothetical protein | - |
| APA386B_RS13770 | 150248..150712 | - | 465 | WP_020936773.1 | hypothetical protein | - |
| APA386B_RS13775 | 150849..151259 | - | 411 | WP_035362716.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| APA386B_RS13780 | 151256..151528 | - | 273 | WP_003626741.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| APA386B_RS13785 | 151601..152017 | - | 417 | WP_003626740.1 | hypothetical protein | - |
| APA386B_RS13790 | 152014..152454 | - | 441 | WP_003626739.1 | hypothetical protein | - |
| APA386B_RS13795 | 152517..153005 | - | 489 | Protein_170 | single-stranded DNA-binding protein | - |
| APA386B_RS15260 | 153663..153809 | - | 147 | WP_003626735.1 | hypothetical protein | - |
| APA386B_RS15265 | 153878..154024 | - | 147 | WP_157884547.1 | hypothetical protein | - |
| APA386B_RS15430 | 154095..154241 | - | 147 | WP_020936778.1 | hypothetical protein | - |
| APA386B_RS13805 | 154234..154536 | - | 303 | WP_003626733.1 | hypothetical protein | - |
| APA386B_RS13810 | 154769..155077 | + | 309 | WP_035362714.1 | hypothetical protein | - |
| APA386B_RS13820 | 155519..155797 | + | 279 | WP_003626728.1 | hypothetical protein | - |
| APA386B_RS13825 | 155921..156496 | + | 576 | WP_003626726.1 | MucR family transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..194780 | 194780 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 20181.21 Da Isoelectric Point: 5.5500
>T29894 WP_035362716.1 NC_021976:c151259-150849 [Acetobacter pasteurianus 386B]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 411 bp
>T29894 NC_021976:c151259-150849 [Acetobacter pasteurianus 386B]
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Antitoxin
Download Length: 91 a.a. Molecular weight: 13411.09 Da Isoelectric Point: 5.5500
>AT29894 WP_003626741.1 NC_021976:c151528-151256 [Acetobacter pasteurianus 386B]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFF
Download Length: 273 bp
>AT29894 NC_021976:c151528-151256 [Acetobacter pasteurianus 386B]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|