Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 123742..124124 Replicon plasmid Apa386Bp1
Accession NC_021976
Organism Acetobacter pasteurianus 386B

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag APA386B_RS15120 Protein ID WP_081939029.1
Coordinates 123969..124124 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag APA386B_RS13635 Protein ID WP_040133421.1
Coordinates 123742..123984 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APA386B_RS14900 119616..119786 - 171 WP_099541955.1 transposase -
APA386B_RS13610 120206..120451 - 246 WP_019092505.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
APA386B_RS14530 121007..121360 - 354 WP_035362748.1 protease inhibitor I42 family protein -
APA386B_RS13620 121625..122074 - 450 WP_003626877.1 hypothetical protein -
APA386B_RS13625 122645..123136 - 492 WP_020936751.1 type II toxin-antitoxin system YhaV family toxin -
APA386B_RS13630 123139..123471 - 333 WP_020936752.1 type II toxin-antitoxin system PrlF family antitoxin -
APA386B_RS13635 123742..123984 + 243 WP_040133421.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
APA386B_RS15120 123969..124124 + 156 WP_081939029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APA386B_RS13640 124127..125212 + 1086 WP_020936754.1 hypothetical protein -
APA386B_RS15125 125225..125779 - 555 Protein_136 cell filamentation protein Fic -
APA386B_RS14920 125829..126133 - 305 Protein_137 type II toxin-antitoxin system PemK/MazF family toxin -
APA386B_RS13650 126428..128488 - 2061 WP_035362896.1 NgoFVII family restriction endonuclease -
APA386B_RS15255 128838..128975 - 138 WP_157884548.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..194780 194780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(10-64)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(8-60)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 6683.07 Da        Isoelectric Point: 12.5075

>T29893 WP_081939029.1 NC_021976:123969-124124 [Acetobacter pasteurianus 386B]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 156 bp

>T29893 NC_021976:123969-124124 [Acetobacter pasteurianus 386B]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 10400.12 Da        Isoelectric Point: 12.7030

>AT29893 WP_040133421.1 NC_021976:123742-123984 [Acetobacter pasteurianus 386B]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
K

Download         Length: 243 bp

>AT29893 NC_021976:123742-123984 [Acetobacter pasteurianus 386B]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References