Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 835095..835732 Replicon plasmid pRetMIM1f
Accession NC_021911
Organism Rhizobium etli bv. mimosae str. Mim1

Toxin (Protein)


Gene name vapC Uniprot ID S5S8S3
Locus tag REMIM1_RS33290 Protein ID WP_020919781.1
Coordinates 835331..835732 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID S5SX58
Locus tag REMIM1_RS33285 Protein ID WP_020919780.1
Coordinates 835095..835331 (+) Length 79 a.a.

Genomic Context

REMIM1_RS33270REMIM1_RS33275REMIM1_RS33285REMIM1_RS33290REMIM1_RS33300REMIM1_RS37335REMIM1_RS33310REMIM1_RS33315REMIM1_RS33320REMIM1_RS33280REMIM1_RS33295
Location: 830932..832107 (1176 bp)
Type: Others
Protein ID: WP_020919777.1
Location: 832116..833147 (1032 bp)
Type: Others
Protein ID: WP_020919778.1
Location: 835095..835331 (237 bp)
Type: Antitoxin
Protein ID: WP_020919780.1
Location: 835331..835732 (402 bp)
Type: Toxin
Protein ID: WP_020919781.1
Location: 836662..836985 (324 bp)
Type: Others
Protein ID: WP_008530485.1
Location: 837300..837467 (168 bp)
Type: Others
Protein ID: WP_196232147.1
Location: 837801..838271 (471 bp)
Type: Others
Protein ID: WP_020919784.1
Location: 838449..838718 (270 bp)
Type: Others
Protein ID: WP_020919785.1
Location: 838715..839128 (414 bp)
Type: Others
Protein ID: WP_020919786.1
Location: 833300..834508 (1209 bp)
Type: Others
Protein ID: WP_041679331.1
Location: 835867..836199 (333 bp)
Type: Others
Protein ID: WP_020919782.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
REMIM1_RS33270830932..832107+1176WP_020919777.1type IV secretion system protein VirB10-
REMIM1_RS33275832116..833147+1032WP_020919778.1P-type DNA transfer ATPase VirB11-
REMIM1_RS33280833300..834508-1209WP_041679331.1DUF1173 domain-containing protein-
REMIM1_RS33285835095..835331+237WP_020919780.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
REMIM1_RS33290835331..835732+402WP_020919781.1type II toxin-antitoxin system VapC family toxinToxin
REMIM1_RS33295835867..836199-333WP_020919782.1WGR domain-containing protein-
REMIM1_RS33300836662..836985+324WP_008530485.1DUF736 family protein-
REMIM1_RS37335837300..837467+168WP_196232147.1hypothetical protein-
REMIM1_RS33310837801..838271+471WP_020919784.1hypothetical protein-
REMIM1_RS33315838449..838718+270WP_020919785.1type II toxin-antitoxin system prevent-host-death family antitoxin-
REMIM1_RS33320838715..839128+414WP_020919786.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-htpB1..10826591082659


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14912.15 Da        Isoelectric Point: 4.9309

>T29888 WP_020919781.1 NC_021911:835331-835732 [Rhizobium etli bv. mimosae str. Mim1]
MPLYMLDTNMCIYLMKEQPPQVARRFAECRVGDVVMSAITFAELEYGVSATANAEKERANLEFLIEAIPVAPFDANAARA
YGSVRFATRERKKDHLDKLIAAHALSIDAVLVTNNTRDFSVYEGLPIENWLLS

Download         Length: 402 bp

>T29888 NC_021911:835331-835732 [Rhizobium etli bv. mimosae str. Mim1]
ATGCCGCTTTATATGCTCGACACGAACATGTGTATCTACCTGATGAAGGAGCAGCCGCCGCAAGTCGCGCGCCGCTTTGC
TGAATGCCGCGTCGGTGACGTTGTTATGTCAGCCATTACATTTGCTGAACTTGAATATGGTGTCTCTGCCACGGCGAACG
CGGAAAAGGAGCGGGCAAACCTGGAATTCCTGATAGAGGCGATTCCAGTTGCGCCCTTCGACGCCAATGCGGCGCGGGCC
TACGGGTCCGTCAGATTTGCCACGCGCGAACGGAAAAAAGACCATCTGGACAAATTGATAGCCGCTCATGCGCTCTCGAT
TGATGCGGTCCTCGTGACCAACAATACGCGGGACTTTTCTGTCTATGAAGGGTTGCCGATTGAGAACTGGTTGTTGTCGT
GA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8907.01 Da        Isoelectric Point: 5.8451

>AT29888 WP_020919780.1 NC_021911:835095-835331 [Rhizobium etli bv. mimosae str. Mim1]
VHTTKVFKNGNSQAVRIPADLAYSQTEMDLEIERIGDEIRIRPLKPSLEGVLSRFARFDRSFMAEGRGNQEQTERDAL

Download         Length: 237 bp

>AT29888 NC_021911:835095-835331 [Rhizobium etli bv. mimosae str. Mim1]
GTGCACACGACCAAGGTATTCAAAAACGGCAACTCACAAGCTGTGCGCATCCCTGCGGATTTGGCTTACAGCCAGACCGA
GATGGACCTTGAAATCGAGCGAATCGGTGACGAGATTCGCATACGCCCGCTGAAGCCGTCCCTGGAAGGCGTGCTTTCGC
GTTTCGCAAGGTTTGACCGCTCGTTCATGGCAGAAGGACGCGGTAATCAGGAGCAGACCGAGCGGGATGCGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBS5S8S3

Antitoxin

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Source
ID
Structure
AlphaFold DBS5SX58

References