Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 196792..197459 Replicon plasmid pRetMIM1f
Accession NC_021911
Organism Rhizobium etli bv. mimosae str. Mim1

Toxin (Protein)


Gene name vapC Uniprot ID S5S702
Locus tag REMIM1_RS30335 Protein ID WP_020919222.1
Coordinates 196792..197235 (-) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag REMIM1_RS30340 Protein ID WP_155249506.1
Coordinates 197232..197459 (-) Length 76 a.a.

Genomic Context

REMIM1_RS30325REMIM1_RS30330REMIM1_RS30350REMIM1_RS30360REMIM1_RS36260REMIM1_RS36250REMIM1_RS30310REMIM1_RS30320REMIM1_RS30335REMIM1_RS30340REMIM1_RS30345REMIM1_RS30355REMIM1_RS36885
Location: 195547..195975 (429 bp)
Type: Others
Protein ID: WP_020919219.1
Location: 196010..196450 (441 bp)
Type: Others
Protein ID: WP_155249505.1
Location: 198249..199138 (890 bp)
Type: Others
Protein ID: Protein_184
Location: 200119..201057 (939 bp)
Type: Others
Protein ID: Protein_186
Location: 201315..201665 (351 bp)
Type: Others
Protein ID: Protein_187
Location: 192293..192570 (278 bp)
Type: Others
Protein ID: Protein_176
Location: 193001..194176 (1176 bp)
Type: Others
Protein ID: WP_020919216.1
Location: 194565..195470 (906 bp)
Type: Others
Protein ID: WP_020919218.1
Location: 196792..197235 (444 bp)
Type: Toxin
Protein ID: WP_020919222.1
Location: 197232..197459 (228 bp)
Type: Antitoxin
Protein ID: WP_155249506.1
Location: 197941..198159 (219 bp)
Type: Others
Protein ID: WP_020919224.1
Location: 199263..199475 (213 bp)
Type: Others
Protein ID: WP_020919226.1
Location: 201755..202387 (633 bp)
Type: Others
Protein ID: WP_020919227.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
REMIM1_RS36250192293..192570-278Protein_176LysR family transcriptional regulator-
REMIM1_RS30310193001..194176-1176WP_020919216.1alpha/beta fold hydrolase-
REMIM1_RS30320194565..195470-906WP_020919218.1SDR family oxidoreductase-
REMIM1_RS30325195547..195975+429WP_020919219.1helix-turn-helix transcriptional regulator-
REMIM1_RS30330196010..196450+441WP_155249505.1amidohydrolase family protein-
REMIM1_RS30335196792..197235-444WP_020919222.1PIN domain-containing proteinToxin
REMIM1_RS30340197232..197459-228WP_155249506.1CopG family transcriptional regulatorAntitoxin
REMIM1_RS30345197941..198159-219WP_020919224.1helix-turn-helix domain-containing protein-
REMIM1_RS30350198249..199138+890Protein_184LysR family transcriptional regulator-
REMIM1_RS30355199263..199475-213WP_020919226.1DUF2283 domain-containing protein-
REMIM1_RS30360200119..201057+939Protein_186ISNCY family transposase-
REMIM1_RS36260201315..201665+351Protein_187IS30 family transposase-
REMIM1_RS36885201755..202387-633WP_020919227.1DUF433 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-htpB1..10826591082659
-flankIS/Tn--200113..201057944


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15524.67 Da        Isoelectric Point: 6.6009

>T29886 WP_020919222.1 NC_021911:c197235-196792 [Rhizobium etli bv. mimosae str. Mim1]
VTFLLDVHVLIALIDPGHVAHDDAHEWFAATGQAAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVRKLRSLPGHSF
WPDDVSLVGSGDIDPTRILTPGQVTDTYLLALAKAHGGQLATFDRKLSAAAVTRGNSALHLITASGS

Download         Length: 444 bp

>T29886 NC_021911:c197235-196792 [Rhizobium etli bv. mimosae str. Mim1]
GTGACCTTCCTGCTCGACGTCCATGTGCTGATTGCCTTGATCGATCCGGGTCATGTAGCCCATGATGATGCGCACGAGTG
GTTTGCGGCGACGGGTCAGGCCGCTTGGGCTACCTGCCCCATTACCGAGAATGGTGTCATCCGGATTGTCGGCAACCCCA
AATATCCCAACTCTCCCGGCTCACCGTCACTCGTGATGGAGATCGTCCGCAAATTGCGGTCGCTCCCCGGTCACAGTTTT
TGGCCGGACGATGTGAGCCTTGTCGGTTCAGGTGATATCGATCCTACGAGAATCCTAACACCGGGCCAGGTGACTGACAC
CTATCTGCTTGCACTAGCTAAAGCGCATGGGGGCCAGCTGGCGACATTCGATCGCAAGCTGTCAGCAGCAGCGGTTACAA
GGGGCAATTCTGCCTTGCACCTGATCACCGCGAGTGGATCGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8170.40 Da        Isoelectric Point: 7.0120

>AT29886 WP_155249506.1 NC_021911:c197459-197232 [Rhizobium etli bv. mimosae str. Mim1]
MRTTLAIDDDVLIAAKAMATQQHRSVGEVISELARRSLRRPPSSGERNGIPLLSARPDAPLVTLEIVNALRDELP

Download         Length: 228 bp

>AT29886 NC_021911:c197459-197232 [Rhizobium etli bv. mimosae str. Mim1]
ATGAGAACGACCTTGGCAATTGACGACGATGTCCTGATCGCCGCAAAAGCGATGGCAACCCAGCAGCACCGGAGCGTCGG
CGAAGTCATTTCTGAGCTGGCGAGACGTTCTCTGCGCCGACCGCCCAGCAGCGGCGAGCGCAATGGCATTCCTCTCCTGT
CAGCTCGGCCGGATGCGCCGCTAGTGACGCTCGAAATCGTGAACGCCTTGCGTGACGAACTGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBS5S702

Antitoxin

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Source
ID
Structure
No matching records found

References