Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 168618..169198 Replicon plasmid pRetMIM1f
Accession NC_021911
Organism Rhizobium etli bv. mimosae str. Mim1

Toxin (Protein)


Gene name vapC Uniprot ID S5SW98
Locus tag REMIM1_RS30180 Protein ID WP_020919193.1
Coordinates 168618..169001 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag REMIM1_RS30185 Protein ID WP_041679282.1
Coordinates 168998..169198 (-) Length 67 a.a.

Genomic Context

REMIM1_RS30175REMIM1_RS30190REMIM1_RS30195REMIM1_RS30200REMIM1_RS30205REMIM1_RS30210REMIM1_RS30180REMIM1_RS30185
Location: 167961..168455 (495 bp)
Type: Others
Protein ID: WP_155249485.1
Location: 169547..169990 (444 bp)
Type: Others
Protein ID: WP_020919194.1
Location: 169990..171384 (1395 bp)
Type: Others
Protein ID: WP_020919195.1
Location: 171381..171797 (417 bp)
Type: Others
Protein ID: WP_020919196.1
Location: 171794..172501 (708 bp)
Type: Others
Protein ID: WP_020919197.1
Location: 172498..173487 (990 bp)
Type: Others
Protein ID: WP_020919198.1
Location: 168618..169001 (384 bp)
Type: Toxin
Protein ID: WP_020919193.1
Location: 168998..169198 (201 bp)
Type: Antitoxin
Protein ID: WP_041679282.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
REMIM1_RS30175167961..168455+495WP_155249485.1hypothetical protein-
REMIM1_RS30180168618..169001-384WP_020919193.1type II toxin-antitoxin system VapC family toxinToxin
REMIM1_RS30185168998..169198-201WP_041679282.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
REMIM1_RS30190169547..169990+444WP_020919194.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit-
REMIM1_RS30195169990..171384+1395WP_020919195.1acetyl-CoA carboxylase biotin carboxylase subunit-
REMIM1_RS30200171381..171797+417WP_020919196.1hypothetical protein-
REMIM1_RS30205171794..172501+708WP_020919197.15-oxoprolinase subunit PxpB-
REMIM1_RS30210172498..173487+990WP_020919198.1biotin-dependent carboxyltransferase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-htpB1..10826591082659


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14273.45 Da        Isoelectric Point: 6.6036

>T29885 WP_020919193.1 NC_021911:c169001-168618 [Rhizobium etli bv. mimosae str. Mim1]
VILVDTSIWIDHFRHRDAELSKIIEEDRLLCHPFVIGELALGSLRDRDAVMAFLAAQREAFIATHDEVMTMIDRHLIFSM
GIGYTDAHLLASTLLDRRSTLWTRDKRLAAAAQKAGASLHVPVNTPN

Download         Length: 384 bp

>T29885 NC_021911:c169001-168618 [Rhizobium etli bv. mimosae str. Mim1]
GTGATACTGGTTGACACCTCAATTTGGATTGATCATTTCCGCCATAGAGACGCCGAATTAAGCAAAATTATCGAAGAAGA
TCGCCTACTCTGCCACCCTTTCGTAATCGGCGAGTTGGCGCTTGGCAGTCTTCGGGATCGTGATGCCGTGATGGCTTTCC
TAGCGGCGCAGCGGGAAGCATTTATCGCAACGCACGATGAGGTCATGACGATGATCGATCGACATTTGATCTTCAGCATG
GGGATTGGCTATACGGATGCGCACCTGCTGGCTTCGACGCTGCTCGACCGGCGGTCGACTTTGTGGACAAGAGACAAGCG
CCTGGCAGCAGCGGCTCAAAAGGCAGGCGCGTCACTTCATGTACCCGTGAACACACCCAACTAG

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7190.32 Da        Isoelectric Point: 11.4483

>AT29885 WP_041679282.1 NC_021911:c169198-168998 [Rhizobium etli bv. mimosae str. Mim1]
MRSTINLDDNLIKRARSLTGTKETAALVRQALETLVRVESGKRLVALGGTMPDAEAAPRRRSEAVK

Download         Length: 201 bp

>AT29885 NC_021911:c169198-168998 [Rhizobium etli bv. mimosae str. Mim1]
ATGCGATCTACCATTAATCTCGACGACAACCTCATTAAAAGAGCGAGGTCTCTAACCGGCACGAAGGAAACGGCTGCGCT
TGTCCGTCAAGCATTGGAGACACTCGTACGGGTCGAGTCCGGAAAGCGCCTCGTTGCACTTGGGGGCACCATGCCCGACG
CAGAGGCAGCCCCTCGTCGGCGGAGTGAAGCGGTCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBS5SW98

Antitoxin

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Source
ID
Structure
No matching records found

References