Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 339058..339755 Replicon plasmid pRetMIM1d
Accession NC_021908
Organism Rhizobium etli bv. mimosae str. Mim1

Toxin (Protein)


Gene name vapC Uniprot ID S5STF9
Locus tag REMIM1_RS25815 Protein ID WP_011428150.1
Coordinates 339058..339504 (-) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID S5S4P1
Locus tag REMIM1_RS25820 Protein ID WP_011428151.1
Coordinates 339501..339755 (-) Length 85 a.a.

Genomic Context

REMIM1_RS25795REMIM1_RS25805REMIM1_RS25810REMIM1_RS25830REMIM1_RS25800REMIM1_RS25815REMIM1_RS25820REMIM1_RS25825
Location: 334860..336152 (1293 bp)
Type: Others
Protein ID: WP_011428146.1
Location: 336785..337654 (870 bp)
Type: Others
Protein ID: WP_020923146.1
Location: 337828..339036 (1209 bp)
Type: Others
Protein ID: WP_020923147.1
Location: 340816..341673 (858 bp)
Type: Others
Protein ID: WP_020923149.1
Location: 336218..336676 (459 bp)
Type: Others
Protein ID: WP_020923145.1
Location: 339058..339504 (447 bp)
Type: Toxin
Protein ID: WP_011428150.1
Location: 339501..339755 (255 bp)
Type: Antitoxin
Protein ID: WP_011428151.1
Location: 339826..340665 (840 bp)
Type: Others
Protein ID: WP_020923148.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
REMIM1_RS25795334860..336152+1293WP_011428146.1L-rhamnose catabolism isomerase-
REMIM1_RS25800336218..336676-459WP_020923145.1carboxymuconolactone decarboxylase family protein-
REMIM1_RS25805336785..337654+870WP_020923146.1sigma-70 family RNA polymerase sigma factor-
REMIM1_RS25810337828..339036+1209WP_020923147.1amidohydrolase/deacetylase family metallohydrolase-
REMIM1_RS25815339058..339504-447WP_011428150.1type II toxin-antitoxin system VapC family toxinToxin
REMIM1_RS25820339501..339755-255WP_011428151.1plasmid stabilization proteinAntitoxin
REMIM1_RS25825339826..340665-840WP_020923148.1IclR family transcriptional regulator-
REMIM1_RS25830340816..341673+858WP_020923149.1SDR family oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..512054512054


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15986.25 Da        Isoelectric Point: 6.8809

>T29884 WP_011428150.1 NC_021908:c339504-339058 [Rhizobium etli bv. mimosae str. Mim1]
MIVLDTNVLSEAMKPTPHSAVRSWLNEQVAETLYLSSVTLAELLFGIGALPDGRRKTALTETLGGVLELFRARVLSFDAE
AARHYADLAIRARAGGKGFPTPDGYIAAIASSKGFMVATRDVSPFEAAGLTVVNPWNHQTPHAFRTDF

Download         Length: 447 bp

>T29884 NC_021908:c339504-339058 [Rhizobium etli bv. mimosae str. Mim1]
ATGATCGTTCTGGATACGAACGTTCTTTCCGAGGCGATGAAACCAACCCCTCATTCGGCTGTGCGGTCATGGCTGAACGA
GCAGGTTGCCGAGACCTTGTATTTGTCGAGTGTGACGTTGGCCGAGCTGCTGTTTGGCATCGGCGCGCTGCCGGACGGTC
GGCGCAAGACGGCTCTAACCGAAACACTCGGCGGCGTACTCGAACTGTTCCGGGCTCGCGTGTTGTCGTTCGACGCGGAA
GCGGCCCGACATTATGCCGATCTTGCCATCAGGGCTCGTGCGGGCGGCAAAGGATTTCCAACTCCGGACGGATATATCGC
CGCCATCGCTTCTTCGAAGGGGTTTATGGTCGCAACACGTGACGTCAGCCCTTTTGAAGCCGCGGGACTTACTGTCGTAA
ATCCCTGGAACCACCAAACACCTCATGCCTTTCGGACGGATTTCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9429.67 Da        Isoelectric Point: 5.7252

>AT29884 WP_011428151.1 NC_021908:c339755-339501 [Rhizobium etli bv. mimosae str. Mim1]
MAILTVRNVPDEVHRALRLRAAIHGRSTEAEVRDILENAVKPEQRIRMGDALAEIGRQSGLSNADFEGLDQLRDRAPAEP
LRFE

Download         Length: 255 bp

>AT29884 NC_021908:c339755-339501 [Rhizobium etli bv. mimosae str. Mim1]
ATGGCCATTCTGACAGTTCGAAATGTGCCCGATGAGGTGCATCGCGCGTTGCGTCTGCGCGCGGCGATACACGGCCGCAG
CACCGAGGCGGAGGTCCGTGACATCCTGGAAAATGCGGTGAAACCCGAGCAACGTATCCGCATGGGGGATGCCTTGGCCG
AAATCGGTCGACAGTCAGGGCTGTCCAATGCTGATTTCGAAGGGCTCGACCAGCTGCGCGATAGGGCGCCGGCGGAGCCA
TTGAGGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBS5STF9

Antitoxin

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Source
ID
Structure
AlphaFold DBS5S4P1

References