Detailed information of TA system TA029883

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VapB
• Location: 1690083..1690677
• Replicon: chromosome
• Accession: NC_021905
• Organism: Rhizobium etli bv. mimosae str. Mim1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: REMIM1_RS08575
• Protein ID: WP_041678860.1
• Coordinates: 1690083..1690472 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: REMIM1_RS35390
• Protein ID: WP_080655789.1
• Coordinates: 1690456..1690677 (-)
• Length: 74 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
REMIM1_RS08555	1685326..1685946	-	621	WP_020921027.1	glycerol-3-phosphate 1-O-acyltransferase PlsY	-
REMIM1_RS08560	1685992..1687281	-	1290	WP_020921028.1	dihydroorotase	-
REMIM1_RS08565	1687278..1688234	-	957	WP_011424957.1	aspartate carbamoyltransferase catalytic subunit	-
REMIM1_RS08570	1688413..1690071	+	1659	WP_020921029.1	acyl-CoA dehydrogenase family protein	-
REMIM1_RS08575	1690083..1690472	-	390	WP_041678860.1	PIN domain nuclease	Toxin
REMIM1_RS35390	1690456..1690677	-	222	WP_080655789.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
REMIM1_RS08580	1690824..1693709	-	2886	WP_020921031.1	Rne/Rng family ribonuclease	-
REMIM1_RS08585	1694332..1695591	+	1260	WP_041678621.1	N-acetylmuramoyl-L-alanine amidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-120)

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (1-43)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 14745.05 Da
• Isoelectric Point: 6.6425

>T29883 WP_041678860.1 NC_021905:c1690472-1690083 [Rhizobium etli bv. mimosae str. Mim1]
VIVVDSSVWIPHLRGIENAARRRLQNIEDPLEILVGDLILMEVLQGARDDRHATTIEANLRQFTIRPMLDDSLAVRAARN
YRLLRERGITMRKTIDVIIGTFCIQEGHSLLHDDRDFDPMAQHLGLKIA

Nucleotide

• Length: 390 bp

>T29883 NC_021905:c1690472-1690083 [Rhizobium etli bv. mimosae str. Mim1]
GTGATCGTCGTCGATAGTTCGGTCTGGATTCCGCATCTACGTGGGATAGAAAACGCCGCTAGACGGCGTCTGCAGAATAT
CGAAGATCCGCTGGAGATTCTTGTTGGCGATCTTATTCTTATGGAGGTCCTCCAAGGCGCGCGCGATGACCGTCATGCAA
CCACCATCGAAGCGAATTTGCGCCAATTCACGATCCGTCCGATGCTTGACGACAGCCTCGCCGTTAGGGCAGCCCGCAAT
TATCGCCTGCTGCGGGAACGCGGTATCACAATGCGCAAGACCATCGACGTAATCATTGGCACATTCTGCATTCAAGAAGG
CCACTCGCTCTTGCACGATGATAGGGATTTCGATCCCATGGCCCAGCATCTCGGTCTCAAGATCGCCTGA

Antitoxin

Protein

• Length: 74 a.a.
• Molecular weight: 8171.25 Da
• Isoelectric Point: 10.9254

>AT29883 WP_080655789.1 NC_021905:c1690677-1690456 [Rhizobium etli bv. mimosae str. Mim1]
MRTNIDIDDALLHAAMTATGLATKKATIEQALRSLVDRHRRKNAIANLSGIGWEGDLEGMRRDRPEGTSDRRR

Nucleotide

• Length: 222 bp

>AT29883 NC_021905:c1690677-1690456 [Rhizobium etli bv. mimosae str. Mim1]
ATGCGGACGAATATAGATATCGATGATGCCTTGCTCCACGCAGCGATGACCGCCACGGGGTTGGCGACGAAAAAAGCTAC
CATTGAACAGGCCCTCCGAAGCCTCGTCGACAGGCACCGCAGAAAAAATGCGATCGCAAATCTCTCTGGAATCGGCTGGG
AGGGTGATCTGGAAGGGATGCGCCGCGATCGACCGGAAGGAACCAGTGATCGTCGTCGATAG