Detailed information of TA system TA029773

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 3861813..3862379
• Replicon: chromosome
• Accession: NC_021741
• Organism: Serratia liquefaciens ATCC 27592

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: M495_RS18095
• Protein ID: WP_020828125.1
• Coordinates: 3861813..3862118 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: M495_RS18100
• Protein ID: WP_041414825.1
• Coordinates: 3862119..3862379 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M495_RS18075	3858130..3859107	-	978	WP_041414824.1	TIM barrel protein	-
M495_RS18080	3859117..3859824	-	708	WP_020828122.1	GntR family transcriptional regulator	-
M495_RS18085	3860020..3861252	-	1233	WP_020828123.1	MFS transporter	-
M495_RS18090	3861346..3861795	+	450	WP_020828124.1	helix-turn-helix transcriptional regulator	-
M495_RS18095	3861813..3862118	-	306	WP_020828125.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
M495_RS18100	3862119..3862379	-	261	WP_041414825.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
M495_RS18105	3862546..3863331	+	786	WP_020828127.1	23S rRNA pseudouridine(2604) synthase RluF	-
M495_RS18110	3863426..3866494	-	3069	WP_020828128.1	autotransporter domain-containing protein	-
M495_RS18115	3866714..3867028	-	315	WP_041414827.1	lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-62)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11398.91 Da
• Isoelectric Point: 6.4687

>T29773 WP_020828125.1 NC_021741:c3862118-3861813 [Serratia liquefaciens ATCC 27592]
MASYRLTGEAQSDILEIRDYTLSNWGIQQSRDYLVRLCQGLTNLTEIPGIGQHRVEDPGNGVYSFPYLSHMIYYATANSE
ITILAVLHQSCVPAKHLSQRL

Nucleotide

• Length: 306 bp

>T29773 NC_021741:c3862118-3861813 [Serratia liquefaciens ATCC 27592]
ATGGCCAGTTACCGACTGACCGGTGAGGCGCAAAGCGATATCCTGGAGATTCGCGACTACACATTGAGCAACTGGGGCAT
ACAGCAATCCAGAGATTACCTTGTAAGACTGTGCCAAGGATTAACCAACCTGACGGAAATACCAGGCATTGGGCAGCATC
GAGTCGAGGATCCAGGGAACGGTGTTTATAGCTTTCCCTACCTCAGCCATATGATTTATTACGCTACAGCAAACAGCGAA
ATTACCATTCTTGCAGTTTTGCACCAAAGCTGCGTTCCAGCCAAACATCTGTCTCAGCGGCTGTAG

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9582.99 Da
• Isoelectric Point: 4.7469

>AT29773 WP_041414825.1 NC_021741:c3862379-3862119 [Serratia liquefaciens ATCC 27592]
MHILTANEAKTQFGDLLLKVPGEPVQITRNGKPVAVVVSAEDYEQIEAMKLQLLQMKIQRSQHDMAIGNTVDGETFFSEL
LEQNKG

Nucleotide

• Length: 261 bp

>AT29773 NC_021741:c3862379-3862119 [Serratia liquefaciens ATCC 27592]
ATGCATATTCTGACAGCCAATGAAGCCAAAACCCAGTTTGGCGATTTGCTGCTTAAGGTTCCGGGTGAACCGGTGCAAAT
CACCCGTAATGGCAAGCCCGTTGCGGTTGTGGTGTCTGCCGAAGATTACGAGCAAATTGAAGCGATGAAACTCCAACTGT
TACAAATGAAGATTCAGCGTTCCCAGCATGATATGGCGATCGGCAATACCGTTGATGGCGAGACGTTTTTCTCTGAACTG
CTGGAGCAGAATAAAGGATAA