Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 845547..846106 Replicon chromosome
Accession NC_021741
Organism Serratia liquefaciens ATCC 27592

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag M495_RS03875 Protein ID WP_020825340.1
Coordinates 845547..845840 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M495_RS03880 Protein ID WP_020825341.1
Coordinates 845828..846106 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M495_RS03855 840594..841544 - 951 WP_020825336.1 acetyltransferase -
M495_RS03860 841541..843286 - 1746 WP_020825337.1 aerobactin synthase IucA -
M495_RS03865 843424..844647 + 1224 WP_041414246.1 MFS transporter -
M495_RS03870 844653..845537 + 885 WP_041414248.1 siderophore-interacting protein -
M495_RS03875 845547..845840 - 294 WP_020825340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M495_RS03880 845828..846106 - 279 WP_020825341.1 ribbon-helix-helix protein, CopG family Antitoxin
M495_RS03885 846196..846579 - 384 WP_041415223.1 oxalurate catabolism protein HpxZ -
M495_RS03890 846583..847983 - 1401 WP_020825343.1 AtzE family amidohydrolase -
M495_RS03895 847980..848171 - 192 WP_020825344.1 oxalurate catabolism protein HpxX -
M495_RS03900 848199..849785 - 1587 WP_020825345.1 gamma-glutamyltransferase -
M495_RS03905 849932..850771 + 840 WP_020825346.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10918.40 Da        Isoelectric Point: 6.8772

>T29761 WP_020825340.1 NC_021741:c845840-845547 [Serratia liquefaciens ATCC 27592]
VPQLIWTPAALLDIQRLYQFLAAKDRQAAQKTVASIRSSINILAHHPQAGRPIEDMEIEFREWPNNFGNSGYIIALYHFD
GSTAVLLAVRHQSEAGY

Download         Length: 294 bp

>T29761 NC_021741:c845840-845547 [Serratia liquefaciens ATCC 27592]
GTGCCACAACTGATATGGACGCCTGCCGCACTGCTCGATATTCAGCGACTGTACCAATTTCTGGCAGCCAAAGATCGCCA
GGCTGCGCAAAAGACCGTGGCATCCATTCGTAGCAGCATCAATATCCTGGCCCATCATCCTCAGGCCGGTCGGCCCATTG
AAGATATGGAAATTGAATTTAGGGAATGGCCGAACAATTTCGGCAACAGCGGCTATATTATTGCCCTGTATCATTTTGAT
GGCAGCACCGCTGTACTGCTGGCAGTGCGCCATCAAAGTGAAGCCGGTTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10828.97 Da        Isoelectric Point: 5.6257

>AT29761 WP_020825341.1 NC_021741:c846106-845828 [Serratia liquefaciens ATCC 27592]
MTTATSIKIDDELKQRVQQIAATRQRSAHWIVREAIREYVEREEKREALRKDALQARETYQTNGKHLTQDEADHWLANLE
KGDDTEIPECHN

Download         Length: 279 bp

>AT29761 NC_021741:c846106-845828 [Serratia liquefaciens ATCC 27592]
ATGACTACGGCTACATCGATAAAAATTGATGATGAGCTCAAGCAACGGGTGCAACAAATCGCGGCCACGCGTCAGCGAAG
TGCGCACTGGATTGTGCGCGAGGCTATCCGTGAATACGTCGAGCGAGAAGAAAAGCGCGAAGCGCTGCGCAAAGACGCAC
TGCAAGCCAGGGAAACGTATCAGACCAATGGTAAACATCTGACCCAAGACGAGGCTGACCATTGGCTCGCTAATCTGGAA
AAAGGTGATGATACGGAGATACCGGAGTGCCACAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References