Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/-
Location 3816171..3816910 Replicon chromosome
Accession UFRD01000002
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain NCTC12023

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NCTC12023_04048 Protein ID SUH99305.1
Coordinates 3816425..3816910 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag NCTC12023_04047 Protein ID SUH99304.1
Coordinates 3816171..3816437 (+) Length 89 a.a.

Genomic Context

NCTC12023_04042NCTC12023_04043NCTC12023_04044NCTC12023_04046NCTC12023_04047NCTC12023_04048NCTC12023_04052NCTC12023_04049NCTC12023_04051NCTC12023_04053NCTC12023_04054
Location: 3811445..3811747 (303 bp)
Type: Others
Protein ID: SUH99300.1
Location: 3811886..3812797 (912 bp)
Type: Others
Protein ID: SUH99301.1
Location: 3812807..3814876 (2070 bp)
Type: Others
Protein ID: SUH99302.1
Location: 3815505..3815972 (468 bp)
Type: Others
Protein ID: SUH99303.1
Location: 3816171..3816437 (267 bp)
Type: Antitoxin
Protein ID: SUH99304.1
Location: 3816425..3816910 (486 bp)
Type: Toxin
Protein ID: SUH99305.1
Location: 3819225..3819935 (711 bp)
Type: Others
Protein ID: SUH99308.1
Location: 3817282..3817821 (540 bp)
Type: Others
Protein ID: SUH99306.1
Location: 3818496..3818828 (333 bp)
Type: Others
Protein ID: SUH99307.1
Location: 3819985..3820959 (975 bp)
Type: Others
Protein ID: SUH99309.1
Location: 3821178..3821840 (663 bp)
Type: Others
Protein ID: SUH99310.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NCTC12023_040423811445..3811747+303SUH99300.1membrane protein-
NCTC12023_040433811886..3812797+912SUH99301.1glycine-tRNA synthetase subunit alpha-
NCTC12023_040443812807..3814876+2070SUH99302.1glycine-tRNA synthetase subunit beta-
NCTC12023_040463815505..3815972+468SUH99303.1acetyltransferase-
NCTC12023_040473816171..3816437+267SUH99304.1Uncharacterized protein conserved in bacteriaAntitoxin
NCTC12023_040483816425..3816910+486SUH99305.1N-acetyltransferase GCN5Toxin
NCTC12023_040493817282..3817821-540SUH99306.1putative exported protein-
NCTC12023_040513818496..3818828-333SUH99307.1putative DNA-binding protein-
NCTC12023_040523819225..3819935+711SUH99308.1Lipoprotein-
NCTC12023_040533819985..3820959-975SUH99309.12-hydroxyacid dehydrogenase-
NCTC12023_040543821178..3821840-663SUH99310.1outer membrane protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(31-152)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17703.41 Da        Isoelectric Point: 9.8719

>T297240 SUH99305.1 UFRD01000002:3816425-3816910 [Salmonella enterica subsp. enterica serovar Typhimurium]
VGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAARTFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNM
PDPIPVIILARLAVDLSFHGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKSSQTQQRTLFLRLP
Q

Download         Length: 486 bp

>T297240 UFRD01000002:3816425-3816910 [Salmonella enterica subsp. enterica serovar Typhimurium]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10141.55 Da        Isoelectric Point: 4.5256

>AT297240 SUH99304.1 UFRD01000002:3816171-3816437 [Salmonella enterica subsp. enterica serovar Typhimurium]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILETACQAAEKVILDRRVFNFNDEQYEEFINLLDAPVADDPVIEKLL
ARKPQWDV

Download         Length: 267 bp

>AT297240 UFRD01000002:3816171-3816437 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGATGCAGCTGCGGAAATCCTTCA
CAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCCTTGACCGCCGTGTATTTAACT
TTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGATCCCGTTATCGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References