Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2268747..2269367 Replicon chromosome
Accession UFRD01000002
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain NCTC12023

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag NCTC12023_02523 Protein ID SUH97877.1
Coordinates 2269149..2269367 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag NCTC12023_02522 Protein ID SUH97876.1
Coordinates 2268747..2269121 (+) Length 125 a.a.

Genomic Context

NCTC12023_02519NCTC12023_02520NCTC12023_02521NCTC12023_02522NCTC12023_02523NCTC12023_02524NCTC12023_02525NCTC12023_02527NCTC12023_02529NCTC12023_02526NCTC12023_02530
Location: 2263887..2265080 (1194 bp)
Type: Others
Protein ID: SUH97873.1
Location: 2265103..2265666 (564 bp)
Type: Others
Protein ID: SUH97874.1
Location: 2265663..2268251 (2589 bp)
Type: Others
Protein ID: SUH97875.1
Location: 2268747..2269121 (375 bp)
Type: Antitoxin
Protein ID: SUH97876.1
Location: 2269149..2269367 (219 bp)
Type: Toxin
Protein ID: SUH97877.1
Location: 2269546..2270097 (552 bp)
Type: Others
Protein ID: SUH97878.1
Location: 2270214..2270684 (471 bp)
Type: Others
Protein ID: SUH97879.1
Location: 2271371..2272921 (1551 bp)
Type: Others
Protein ID: SUH97881.1
Location: 2273230..2273541 (312 bp)
Type: Others
Protein ID: SUH97882.1
Location: 2270886..2271146 (261 bp)
Type: Others
Protein ID: SUH97880.1
Location: 2273574..2274143 (570 bp)
Type: Others
Protein ID: SUH97883.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NCTC12023_025192263887..2265080+1194SUH97873.1acriflavin resistance protein A-
NCTC12023_025202265103..2265666+564SUH97874.1acriflavin resistance protein B-
NCTC12023_025212265663..2268251+2589SUH97875.1acriflavin resistance protein B-
NCTC12023_025222268747..2269121+375SUH97876.1Hha toxicity attenuatorAntitoxin
NCTC12023_025232269149..2269367+219SUH97877.1hemolysin expression modulating proteinToxin
NCTC12023_025242269546..2270097+552SUH97878.1maltose O-acetyltransferase-
NCTC12023_025252270214..2270684+471SUH97879.1Putative inner membrane protein-
NCTC12023_025262270886..2271146-261SUH97880.150S ribosomal protein L31-
NCTC12023_025272271371..2272921+1551SUH97881.1Uncharacterized protein ylaB-
NCTC12023_025292273230..2273541+312SUH97882.1methylated-DNA-[protein]-cysteine S-methyltransferase-
NCTC12023_025302273574..2274143-570SUH97883.1lipoprotein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-116)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8613.97 Da        Isoelectric Point: 8.9008

>T297234 SUH97877.1 UFRD01000002:2269149-2269367 [Salmonella enterica subsp. enterica serovar Typhimurium]
MSDKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR

Download         Length: 219 bp

>T297234 UFRD01000002:2269149-2269367 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14453.27 Da        Isoelectric Point: 5.1444

>AT297234 SUH97876.1 UFRD01000002:2268747-2269121 [Salmonella enterica subsp. enterica serovar Typhimurium]
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAVNLQLNELIEHIATFALNYKIKYNEDNKLIAQIDEYL
DDTFMLFSSYGINTQDLQKWRKSGNRLFRCFVNATRANPVSLSC

Download         Length: 375 bp

>AT297234 UFRD01000002:2268747-2269121 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References