Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 3283662..3285170 | Replicon | chromosome |
Accession | NZ_OX638701 | ||
Organism | Pseudomonas aeruginosa strain 4782MK isolate 4782MK |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | QSK41_RS15310 | Protein ID | WP_079276297.1 |
Coordinates | 3283662..3284249 (+) | Length | 196 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | A0A5B3ABU1 |
Locus tag | QSK41_RS15315 | Protein ID | WP_003119683.1 |
Coordinates | 3284316..3285170 (+) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QSK41_RS15305 (PAER4782_15305) | 3279917..3283396 | - | 3480 | WP_003117605.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
QSK41_RS15310 (PAER4782_15310) | 3283662..3284249 | + | 588 | WP_079276297.1 | GNAT family protein | Toxin |
QSK41_RS15315 (PAER4782_15315) | 3284316..3285170 | + | 855 | WP_003119683.1 | AraC family transcriptional regulator | Antitoxin |
QSK41_RS15320 (PAER4782_15320) | 3285267..3287432 | + | 2166 | WP_003115567.1 | TonB-dependent receptor family protein | - |
QSK41_RS15325 (PAER4782_15325) | 3287607..3289481 | + | 1875 | WP_003117607.1 | MFS transporter | - |
QSK41_RS15330 (PAER4782_15335) | 3289542..3289751 | - | 210 | WP_003115568.1 | cold-shock protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21892.22 Da Isoelectric Point: 9.8675
>T297187 WP_079276297.1 NZ_OX638701:3283662-3284249 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQQGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQQGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31875.19 Da Isoelectric Point: 7.5295
>AT297187 WP_003119683.1 NZ_OX638701:3284316-3285170 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTIYE
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTIYE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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