Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 35803..36353 Replicon plasmid p3541_1
Accession NZ_OX638611
Organism Pseudomonas aeruginosa strain 3541 isolate 3541

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QPK16_RS31995 Protein ID WP_034061810.1
Coordinates 36075..36353 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QPK16_RS31990 Protein ID WP_034061812.1
Coordinates 35803..36075 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPK16_RS31960 (JCHGIK_00205) 31114..31779 + 666 WP_034061819.1 hypothetical protein -
QPK16_RS31965 (JCHGIK_00210) 31917..32183 + 267 WP_034061816.1 helix-turn-helix transcriptional regulator -
QPK16_RS31970 (JCHGIK_00215) 32149..32961 + 813 Protein_42 site-specific integrase -
QPK16_RS31975 (JCHGIK_00220) 33123..34271 + 1149 WP_034061814.1 site-specific integrase -
QPK16_RS31980 (JCHGIK_00225) 34413..35159 + 747 WP_034061813.1 DUF2807 domain-containing protein -
QPK16_RS31985 35169..35609 + 441 WP_128734628.1 hypothetical protein -
QPK16_RS31990 (JCHGIK_00230) 35803..36075 + 273 WP_034061812.1 ribbon-helix-helix domain-containing protein Antitoxin
QPK16_RS31995 (JCHGIK_00235) 36075..36353 + 279 WP_034061810.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QPK16_RS32000 (JCHGIK_00240) 36355..37182 + 828 WP_034061809.1 hypothetical protein -
QPK16_RS32005 (JCHGIK_00245) 37196..37438 + 243 WP_034061808.1 hypothetical protein -
QPK16_RS32010 37451..37963 - 513 WP_044305333.1 hypothetical protein -
QPK16_RS32015 (JCHGIK_00250) 37960..39810 - 1851 WP_049267175.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..179283 179283


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10844.46 Da        Isoelectric Point: 8.5041

>T297182 WP_034061810.1 NZ_OX638611:36075-36353 [Pseudomonas aeruginosa]
MELKWTSKALSDLARLYEFLAAVNRPAAARTVQQLTVTPTTLLTNPRIGERLEEFEPRDVRRILVGHYEMRYEIAADSTI
YLLRLWHTREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10054.25 Da        Isoelectric Point: 4.8616

>AT297182 WP_034061812.1 NZ_OX638611:35803-36075 [Pseudomonas aeruginosa]
MAATAKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPH

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References