Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 148793..149343 Replicon plasmid p3796A
Accession NZ_OX638565
Organism Pseudomonas aeruginosa strain 3796A isolate 3796A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QRQ54_RS33465 Protein ID WP_034061810.1
Coordinates 149065..149343 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QRQ54_RS33460 Protein ID WP_034061812.1
Coordinates 148793..149065 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRQ54_RS33430 (PAE3796A_33250) 144104..144769 + 666 WP_034061819.1 hypothetical protein -
QRQ54_RS33435 (PAE3796A_33255) 144907..145173 + 267 WP_034061816.1 helix-turn-helix transcriptional regulator -
QRQ54_RS33440 (PAE3796A_33260) 145139..145951 + 813 Protein_181 site-specific integrase -
QRQ54_RS33445 (PAE3796A_33265) 146113..147261 + 1149 WP_034061814.1 site-specific integrase -
QRQ54_RS33450 (PAE3796A_33270) 147403..148149 + 747 WP_034061813.1 DUF2807 domain-containing protein -
QRQ54_RS33455 148159..148599 + 441 WP_128734628.1 hypothetical protein -
QRQ54_RS33460 (PAE3796A_33275) 148793..149065 + 273 WP_034061812.1 ribbon-helix-helix domain-containing protein Antitoxin
QRQ54_RS33465 (PAE3796A_33280) 149065..149343 + 279 WP_034061810.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QRQ54_RS33470 (PAE3796A_33285) 149345..150172 + 828 WP_034061809.1 hypothetical protein -
QRQ54_RS33475 (PAE3796A_33290) 150186..150428 + 243 WP_034061808.1 hypothetical protein -
QRQ54_RS33480 150441..150953 - 513 WP_044305333.1 hypothetical protein -
QRQ54_RS33485 (PAE3796A_33295) 150950..152800 - 1851 WP_049267175.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..178483 178483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10844.46 Da        Isoelectric Point: 8.5041

>T297175 WP_034061810.1 NZ_OX638565:149065-149343 [Pseudomonas aeruginosa]
MELKWTSKALSDLARLYEFLAAVNRPAAARTVQQLTVTPTTLLTNPRIGERLEEFEPRDVRRILVGHYEMRYEIAADSTI
YLLRLWHTREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10054.25 Da        Isoelectric Point: 4.8616

>AT297175 WP_034061812.1 NZ_OX638565:148793-149065 [Pseudomonas aeruginosa]
MAATAKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPH

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References