Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4898776..4900034 | Replicon | chromosome |
Accession | NZ_OX638564 | ||
Organism | Pseudomonas aeruginosa strain 3796A isolate 3796A |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | QRQ54_RS22895 | Protein ID | WP_003086331.1 |
Coordinates | 4898776..4899531 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | QRQ54_RS22900 | Protein ID | WP_003086329.1 |
Coordinates | 4899666..4900034 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QRQ54_RS22885 (PAE3796A_22725) | 4893944..4896487 | + | 2544 | WP_043543407.1 | acyl-homoserine-lactone acylase QuiP | - |
QRQ54_RS22890 (PAE3796A_22730) | 4896642..4898003 | - | 1362 | WP_003134034.1 | DNA recombination protein RmuC | - |
QRQ54_RS22895 (PAE3796A_22740) | 4898776..4899531 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
QRQ54_RS22900 (PAE3796A_22745) | 4899666..4900034 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
QRQ54_RS22905 (PAE3796A_22750) | 4900107..4901393 | - | 1287 | WP_003134035.1 | FAD-binding oxidoreductase | - |
QRQ54_RS22910 (PAE3796A_22755) | 4901449..4902942 | - | 1494 | WP_003086325.1 | aldehyde dehydrogenase family protein | - |
QRQ54_RS22915 (PAE3796A_22760) | 4903117..4903593 | + | 477 | WP_009877993.1 | elongation factor GreAB | - |
QRQ54_RS22920 (PAE3796A_22765) | 4903596..4903871 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T297172 WP_003086331.1 NZ_OX638564:c4899531-4898776 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT297172 WP_003086329.1 NZ_OX638564:c4900034-4899666 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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