Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2182088..2182356 Replicon chromosome
Accession NZ_OX637964
Organism Escherichia coli O25b:H4-ST131 isolate 46

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2182216..2182318 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2182088..2182356 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQG90_RS10685 2178641..2179303 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQG90_RS10690 2179327..2179983 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QQG90_RS10695 2180085..2180315 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQG90_RS10700 2180454..2180828 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQG90_RS10705 2180832..2181704 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
QQG90_RS10710 2181717..2182058 + 342 WP_000976472.1 YebY family protein -
- 2182088..2182356 - 269 - - Antitoxin
- 2182216..2182318 + 103 - - Toxin
QQG90_RS10715 2182453..2183109 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
QQG90_RS10720 2183110..2183301 - 192 WP_001296140.1 YebW family protein -
QQG90_RS10725 2183406..2183642 - 237 WP_001295499.1 YebV family protein -
QQG90_RS10730 2183759..2185198 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2099726..2198195 98469


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T297146 NZ_OX637964:2182216-2182318 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT297146 NZ_OX637964:c2182356-2182088 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References