Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2129804..2130072 Replicon chromosome
Accession NZ_OX637961
Organism Escherichia coli O25b:H4-ST131 isolate 86

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2129932..2130034 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2129804..2130072 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQG89_RS10170 2126357..2127019 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQG89_RS10175 2127043..2127699 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QQG89_RS10180 2127801..2128031 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQG89_RS10185 2128170..2128544 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQG89_RS10190 2128548..2129420 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
QQG89_RS10195 2129433..2129774 + 342 WP_000976472.1 YebY family protein -
- 2129804..2130072 - 269 - - Antitoxin
- 2129932..2130034 + 103 - - Toxin
QQG89_RS10200 2130169..2130825 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
QQG89_RS10205 2130826..2131017 - 192 WP_001296140.1 YebW family protein -
QQG89_RS10210 2131122..2131358 - 237 WP_001295499.1 YebV family protein -
QQG89_RS10215 2131475..2132914 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T297116 NZ_OX637961:2129932-2130034 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT297116 NZ_OX637961:c2130072-2129804 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References