Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 119027..119598 Replicon plasmid SF1039_p1
Accession NZ_OX461118
Organism Shewanella baltica strain SF1039 isolate SF1039

Toxin (Protein)


Gene name parE Uniprot ID A0A2I8S8S5
Locus tag QOT06_RS22360 Protein ID WP_011918375.1
Coordinates 119287..119598 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1Z3MW28
Locus tag QOT06_RS22355 Protein ID WP_011787805.1
Coordinates 119027..119287 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT06_RS22330 114401..114820 + 420 Protein_131 3'-5' exonuclease -
QOT06_RS22335 115317..116807 + 1491 WP_011787801.1 SulP family inorganic anion transporter -
QOT06_RS22340 116842..117696 + 855 WP_011787802.1 universal stress protein -
QOT06_RS22345 117787..118119 + 333 WP_011787803.1 TraR/DksA C4-type zinc finger protein -
QOT06_RS22350 118237..118857 - 621 WP_011787804.1 recombinase family protein -
QOT06_RS22355 119027..119287 + 261 WP_011787805.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QOT06_RS22360 119287..119598 + 312 WP_011918375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOT06_RS22365 119622..122702 + 3081 WP_011787830.1 Tn3 family transposase -
QOT06_RS22370 122756..123211 + 456 Protein_139 3'-5' exonuclease -
QOT06_RS22375 123208..123699 + 492 WP_249555714.1 hypothetical protein -
QOT06_RS22380 123781..123891 + 111 WP_283631412.1 DUF4113 domain-containing protein -
QOT06_RS22385 123891..124361 + 471 WP_283631413.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..141179 141179


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-61)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11862.70 Da        Isoelectric Point: 8.5341

>T297075 WP_011918375.1 NZ_OX461118:119287-119598 [Shewanella baltica]
MPVTYHLTPDAQSDLIGIHRFTLAQWGTTQSKTYLSGLRQTIQLLAETPTLGKNRPEVRMNVFSFPYSSHVIYYIQHEHQ
FVVFGILHKSMVPLAHLAEREII

Download         Length: 312 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9312.71 Da        Isoelectric Point: 6.4546

>AT297075 WP_011787805.1 NZ_OX461118:119027-119287 [Shewanella baltica]
MNTLSANEAKIHFGDLLLKAQQAPIQINKNGKPVAVVISADAYQSIETLKLHLLQSKAVKAITDIKMGNLVDGNTFFDEL
AAGQYD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I8S8S5

Antitoxin

Source ID Structure
AlphaFold DB A0A1Z3MW28

References