Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4398828..4399497 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QOT07_RS20470 Protein ID WP_099063843.1
Coordinates 4398828..4399250 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2X2G343
Locus tag QOT07_RS20475 Protein ID WP_037418284.1
Coordinates 4399231..4399497 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT07_RS20450 4394712..4395230 + 519 WP_085118696.1 flavodoxin FldB -
QOT07_RS20455 4395271..4396635 - 1365 WP_283603825.1 cell envelope integrity protein CreD -
QOT07_RS20460 4396718..4398136 - 1419 WP_283603826.1 two-component system sensor histidine kinase CreC -
QOT07_RS20465 4398133..4398828 - 696 WP_085118700.1 two-component system response regulator CreB -
QOT07_RS20470 4398828..4399250 - 423 WP_099063843.1 protein YgfX Toxin
QOT07_RS20475 4399231..4399497 - 267 WP_037418284.1 FAD assembly factor SdhE Antitoxin
QOT07_RS20480 4399821..4400813 + 993 WP_099063844.1 tRNA-modifying protein YgfZ -
QOT07_RS20485 4400899..4401573 - 675 WP_085118705.1 hemolysin III family protein -
QOT07_RS20490 4401757..4402365 + 609 WP_099063845.1 HD domain-containing protein -
QOT07_RS20495 4402416..4403741 - 1326 WP_219016887.1 MFS transporter -
QOT07_RS20500 4403738..4404391 - 654 WP_219016888.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16439.32 Da        Isoelectric Point: 10.5155

>T297066 WP_099063843.1 NZ_OX461105:c4399250-4398828 [Serratia proteamaculans]
VAQWRCDVRISWRTQLLSLLTHGALILLILISPWPEGYGPIWLVLLTLVVFECIRSQKRIASRQGELRLLENQRLGWHGQ
EWQLVKQPWMPRYGILLTLQPVGGKKRRRLWLASDAMAKADWRHLRQQLLYPPASDDEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10472.93 Da        Isoelectric Point: 4.7921

>AT297066 WP_037418284.1 NZ_OX461105:c4399497-4399231 [Serratia proteamaculans]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2X2G343

References