Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 4390449..4391175 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QOT07_RS20425 Protein ID WP_283603824.1
Coordinates 4390449..4390835 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QOT07_RS20430 Protein ID WP_085118688.1
Coordinates 4390828..4391175 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT07_RS20400 4385472..4386086 + 615 WP_283603822.1 2OG-Fe dioxygenase family protein -
QOT07_RS20405 4386083..4387312 + 1230 WP_283603823.1 cysteine desulfurase-like protein -
QOT07_RS20415 4387569..4389086 - 1518 WP_207979420.1 lysine--tRNA ligase -
QOT07_RS20425 4390449..4390835 + 387 WP_283603824.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOT07_RS20430 4390828..4391175 + 348 WP_085118688.1 helix-turn-helix domain-containing protein Antitoxin
QOT07_RS20435 4391221..4392954 - 1734 WP_099063838.1 single-stranded-DNA-specific exonuclease RecJ -
QOT07_RS20440 4392961..4393677 - 717 WP_099063839.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QOT07_RS20445 4393705..4394604 - 900 WP_099063840.1 site-specific tyrosine recombinase XerD -
QOT07_RS20450 4394712..4395230 + 519 WP_085118696.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-97)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14809.80 Da        Isoelectric Point: 7.9006

>T297065 WP_283603824.1 NZ_OX461105:4390449-4390835 [Serratia proteamaculans]
MDIFVTDDFDKFMRKNRIFDQRICVAAQEIMHDRHDGDLGGGVYKKRIPINQGKRGGARSVVAFKRGHHQYFVDGWLKNT
VKQTGAKEISDDELETYRELARDFLAMSPEIIQRAVDSGYLREVKCNE

Download         Length: 387 bp

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 13034.05 Da        Isoelectric Point: 11.1355

>AT297065 WP_085118688.1 NZ_OX461105:4390828-4391175 [Serratia proteamaculans]
MNDNRLLRLQKMAQRFNAIGAVSDETVRNIEARVQERESNVRREQAQMMDGARIKMLRERLGLSQADLAAVVNMSTTSVQ
KWERNAVKPQGSALRMLEIIEQKGVASVIISPLDR

Download         Length: 348 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References