Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 4390449..4391175 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QOT07_RS20425 Protein ID WP_283603824.1
Coordinates 4390449..4390835 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QOT07_RS20430 Protein ID WP_085118688.1
Coordinates 4390828..4391175 (+) Length 116 a.a.

Genomic Context

QOT07_RS20400QOT07_RS20405QOT07_RS20425QOT07_RS20430QOT07_RS20450QOT07_RS20415QOT07_RS20435QOT07_RS20440QOT07_RS20445
Location: 4385472..4386086 (615 bp)
Type: Others
Protein ID: WP_283603822.1
Location: 4386083..4387312 (1230 bp)
Type: Others
Protein ID: WP_283603823.1
Location: 4390449..4390835 (387 bp)
Type: Toxin
Protein ID: WP_283603824.1
Location: 4390828..4391175 (348 bp)
Type: Antitoxin
Protein ID: WP_085118688.1
Location: 4394712..4395230 (519 bp)
Type: Others
Protein ID: WP_085118696.1
Location: 4387569..4389086 (1518 bp)
Type: Others
Protein ID: WP_207979420.1
Location: 4391221..4392954 (1734 bp)
Type: Others
Protein ID: WP_099063838.1
Location: 4392961..4393677 (717 bp)
Type: Others
Protein ID: WP_099063839.1
Location: 4393705..4394604 (900 bp)
Type: Others
Protein ID: WP_099063840.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QOT07_RS204004385472..4386086+615WP_283603822.12OG-Fe dioxygenase family protein-
QOT07_RS204054386083..4387312+1230WP_283603823.1cysteine desulfurase-like protein-
QOT07_RS204154387569..4389086-1518WP_207979420.1lysine--tRNA ligase-
QOT07_RS204254390449..4390835+387WP_283603824.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QOT07_RS204304390828..4391175+348WP_085118688.1helix-turn-helix domain-containing proteinAntitoxin
QOT07_RS204354391221..4392954-1734WP_099063838.1single-stranded-DNA-specific exonuclease RecJ-
QOT07_RS204404392961..4393677-717WP_099063839.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
QOT07_RS204454393705..4394604-900WP_099063840.1site-specific tyrosine recombinase XerD-
QOT07_RS204504394712..4395230+519WP_085118696.1flavodoxin FldB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-97)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14809.80 Da        Isoelectric Point: 7.9006

>T297065 WP_283603824.1 NZ_OX461105:4390449-4390835 [Serratia proteamaculans]
MDIFVTDDFDKFMRKNRIFDQRICVAAQEIMHDRHDGDLGGGVYKKRIPINQGKRGGARSVVAFKRGHHQYFVDGWLKNT
VKQTGAKEISDDELETYRELARDFLAMSPEIIQRAVDSGYLREVKCNE

Download         Length: 387 bp

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 13034.05 Da        Isoelectric Point: 11.1355

>AT297065 WP_085118688.1 NZ_OX461105:4390828-4391175 [Serratia proteamaculans]
MNDNRLLRLQKMAQRFNAIGAVSDETVRNIEARVQERESNVRREQAQMMDGARIKMLRERLGLSQADLAAVVNMSTTSVQ
KWERNAVKPQGSALRMLEIIEQKGVASVIISPLDR

Download         Length: 348 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References