Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4021566..4022218 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QOT07_RS18715 Protein ID WP_099062615.1
Coordinates 4021566..4021952 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QOT07_RS18720 Protein ID WP_112348659.1
Coordinates 4021955..4022218 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT07_RS18700 4018034..4019464 + 1431 WP_283603729.1 MFS transporter -
QOT07_RS18705 4019461..4020843 + 1383 WP_099062613.1 two-component system sensor histidine kinase BaeS -
QOT07_RS18710 4020843..4021559 + 717 WP_219016796.1 two-component system response regulator BaeR -
QOT07_RS18715 4021566..4021952 - 387 WP_099062615.1 type II toxin-antitoxin system VapC family toxin Toxin
QOT07_RS18720 4021955..4022218 - 264 WP_112348659.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QOT07_RS18725 4022573..4022911 + 339 WP_099062617.1 YegP family protein -
QOT07_RS18730 4023090..4024442 + 1353 WP_099062618.1 tRNA 5-hydroxyuridine modification protein YegQ -
QOT07_RS18735 4024931..4025848 + 918 WP_283603730.1 lipid kinase YegS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14192.53 Da        Isoelectric Point: 9.5368

>T297064 WP_099062615.1 NZ_OX461105:c4021952-4021566 [Serratia proteamaculans]
MYMFDTNTVSQLFRRHPRLLRVMEKIPPSAVCISSITEAELLYGVAKRQSLALKATVAAFLDSVTVYAWDREAAHCYGTM
RADMAKKGRVMGALDQLIAAHAQSRGATIVTNDKAFAMVPGLRVEDWT

Download         Length: 387 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10206.55 Da        Isoelectric Point: 4.6702

>AT297064 WP_112348659.1 NZ_OX461105:c4022218-4021955 [Serratia proteamaculans]
MERVAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLQMIEQTQVPQDFLVAEDRQQGIAIR
DPFGEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References