Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3563423..3564013 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QOT07_RS16685 Protein ID WP_085117561.1
Coordinates 3563423..3563755 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QOT07_RS16690 Protein ID WP_085117562.1
Coordinates 3563756..3564013 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT07_RS16670 3559272..3559958 + 687 WP_099064588.1 two-component response regulator DpiA -
QOT07_RS16675 3560072..3563161 + 3090 WP_283603601.1 beta-galactosidase -
QOT07_RS16685 3563423..3563755 - 333 WP_085117561.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QOT07_RS16690 3563756..3564013 - 258 WP_085117562.1 antitoxin Antitoxin
QOT07_RS16695 3564361..3564567 - 207 WP_207978181.1 helix-turn-helix transcriptional regulator -
QOT07_RS16700 3564564..3565025 - 462 WP_207978179.1 hypothetical protein -
QOT07_RS16705 3565411..3566673 + 1263 WP_283603604.1 hypothetical protein -
QOT07_RS16710 3566917..3567276 + 360 Protein_3266 ketopantoate reductase C-terminal domain-containing protein -
QOT07_RS16715 3567560..3568537 + 978 WP_283603605.1 DUF1852 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11796.66 Da        Isoelectric Point: 10.4550

>T297062 WP_085117561.1 NZ_OX461105:c3563755-3563423 [Serratia proteamaculans]
MNRGEIWLVSLDPIAGHEQSGKRPVLIVSTASFNKLTRLPVVVPVTSGGNFARTAGFTVSLEGAGVKTTGVIRCDQPRTI
DMGARNGRRLECIPNNVVNEVLARLEAILT

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9367.89 Da        Isoelectric Point: 4.5680

>AT297062 WP_085117562.1 NZ_OX461105:c3564013-3563756 [Serratia proteamaculans]
MYITRLKKVGGSVMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEDDREWINAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References