Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3563423..3564013 Replicon chromosome
Accession NZ_OX461105
Organism Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QOT07_RS16685 Protein ID WP_085117561.1
Coordinates 3563423..3563755 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QOT07_RS16690 Protein ID WP_085117562.1
Coordinates 3563756..3564013 (-) Length 86 a.a.

Genomic Context

QOT07_RS16670QOT07_RS16675QOT07_RS16705QOT07_RS16710QOT07_RS16715QOT07_RS16685QOT07_RS16690QOT07_RS16695QOT07_RS16700
Location: 3559272..3559958 (687 bp)
Type: Others
Protein ID: WP_099064588.1
Location: 3560072..3563161 (3090 bp)
Type: Others
Protein ID: WP_283603601.1
Location: 3565411..3566673 (1263 bp)
Type: Others
Protein ID: WP_283603604.1
Location: 3566917..3567276 (360 bp)
Type: Others
Protein ID: Protein_3266
Location: 3567560..3568537 (978 bp)
Type: Others
Protein ID: WP_283603605.1
Location: 3563423..3563755 (333 bp)
Type: Toxin
Protein ID: WP_085117561.1
Location: 3563756..3564013 (258 bp)
Type: Antitoxin
Protein ID: WP_085117562.1
Location: 3564361..3564567 (207 bp)
Type: Others
Protein ID: WP_207978181.1
Location: 3564564..3565025 (462 bp)
Type: Others
Protein ID: WP_207978179.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QOT07_RS166703559272..3559958+687WP_099064588.1two-component response regulator DpiA-
QOT07_RS166753560072..3563161+3090WP_283603601.1beta-galactosidase-
QOT07_RS166853563423..3563755-333WP_085117561.1type II toxin-antitoxin system PemK/MazF family toxinToxin
QOT07_RS166903563756..3564013-258WP_085117562.1antitoxinAntitoxin
QOT07_RS166953564361..3564567-207WP_207978181.1helix-turn-helix transcriptional regulator-
QOT07_RS167003564564..3565025-462WP_207978179.1hypothetical protein-
QOT07_RS167053565411..3566673+1263WP_283603604.1hypothetical protein-
QOT07_RS167103566917..3567276+360Protein_3266ketopantoate reductase C-terminal domain-containing protein-
QOT07_RS167153567560..3568537+978WP_283603605.1DUF1852 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11796.66 Da        Isoelectric Point: 10.4550

>T297062 WP_085117561.1 NZ_OX461105:c3563755-3563423 [Serratia proteamaculans]
MNRGEIWLVSLDPIAGHEQSGKRPVLIVSTASFNKLTRLPVVVPVTSGGNFARTAGFTVSLEGAGVKTTGVIRCDQPRTI
DMGARNGRRLECIPNNVVNEVLARLEAILT

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9367.89 Da        Isoelectric Point: 4.5680

>AT297062 WP_085117562.1 NZ_OX461105:c3564013-3563756 [Serratia proteamaculans]
MYITRLKKVGGSVMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEDDREWINAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References