Detailed information of TA system TA297055

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 847904..849587
• Replicon: chromosome
• Accession: NZ_OX461105
• Organism: Serratia proteamaculans strain EBP3064 isolate EBP3064

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: QOT07_RS03840
• Protein ID: WP_283602589.1
• Coordinates: 848670..849587 (+)
• Length: 306 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: QOT07_RS03835
• Protein ID: WP_283602588.1
• Coordinates: 847904..848677 (+)
• Length: 258 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QOT07_RS03825	843906..844904	+	999	WP_012005280.1	RNA polymerase sigma factor RpoS	-
QOT07_RS03830	844985..847540	-	2556	WP_283602587.1	DNA mismatch repair protein MutS	-
QOT07_RS03835	847904..848677	+	774	WP_283602588.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
QOT07_RS03840	848670..849587	+	918	WP_283602589.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
QOT07_RS03845	849744..850754	-	1011	WP_283602590.1	hypothetical protein	-
QOT07_RS03850	850790..851761	-	972	WP_261416465.1	aldo/keto reductase	-
QOT07_RS03855	851811..852614	-	804	WP_099062793.1	glucose 1-dehydrogenase	-
QOT07_RS03860	852721..853638	+	918	WP_283602591.1	LysR family transcriptional regulator	-
QOT07_RS03865	854132..854449	+	318	WP_020825274.1	PTS sugar transporter subunit IIB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (14-279)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-93)

Sequences

Toxin

Protein

• Length: 306 a.a.
• Molecular weight: 34615.86 Da
• Isoelectric Point: 5.0738

>T297055 WP_283602589.1 NZ_OX461105:848670-849587 [Serratia proteamaculans]
MDKHSPYYRQVALLLSTLPVVASERCFALKGGTAINLFVRDFPRLSVDIDLAYIPLENRDVALPNVRAALTRIAEILQQQ
AGISAVLQTNNSDEMRIVVYSQQAQIKIEVSPVARGTLYPSEERDVVEAVENEFGFATIQVVSLADLYGGKLCAALDRQH
PRDFYDVKMLLETQGIDRQIFNGFITYLLGHPRPLSEVLNPRWKNISELYANEFNGMTFDMVSLEELNAIPELMVTALKV
QFTQRDCDFLMSFKRGEPDWSLAPENQIQYLPAVRWKLQNIGRMPKEKHIQALVKLEETLAGWIG

Nucleotide

• Length: 918 bp

Antitoxin

Protein

• Length: 258 a.a.
• Molecular weight: 28977.31 Da
• Isoelectric Point: 9.8515

>AT297055 WP_283602588.1 NZ_OX461105:847904-848677 [Serratia proteamaculans]
MSSKLNWLLQNTAPGSLVLQSWLTKNGISPSLANKYMHSDWLQKLRAGVYVRSGREPQWSDAILCLQHQLGVSVHLAGLT
SLTYQGRSHYLQLTRQVIWLCVENKASLPKWFKEFPNVEWLLLSNQKLNMHDGKYLTEVEIKGERLKASVPELAAYEVAN
AVPGSLSFEHAAELFQGLVNLSPRKVEALLQSSRAVQTNRLYLFLADHYAHAWVKRIDKTNIDLGAGKRQIVSGGKLDQK
YQITVPESFVSKEISHG

Nucleotide

• Length: 774 bp