Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sezT-pezT/zeta-couple_hipB
Location 1282521..1283773 Replicon chromosome
Accession NZ_OX461103
Organism Streptococcus agalactiae isolate MRI Z2-149

Toxin (Protein)


Gene name sezT Uniprot ID -
Locus tag QOR71_RS06550 Protein ID WP_000418077.1
Coordinates 1282521..1283297 (-) Length 259 a.a.

Antitoxin (Protein)


Gene name pezT Uniprot ID -
Locus tag QOR71_RS06555 Protein ID WP_000578852.1
Coordinates 1283297..1283773 (-) Length 159 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOR71_RS06535 1277739..1278635 - 897 WP_000161641.1 restriction endonuclease -
QOR71_RS06540 1278660..1281743 - 3084 WP_000569020.1 DEAD/DEAH box helicase -
QOR71_RS06545 1281740..1282528 - 789 WP_000100524.1 SAVED domain-containing protein -
QOR71_RS06550 1282521..1283297 - 777 WP_000418077.1 type II toxin-antitoxin system toxin PezT Toxin
QOR71_RS06555 1283297..1283773 - 477 WP_000578852.1 type II toxin-antitoxin system antitoxin PezA Antitoxin
QOR71_RS06560 1283842..1284132 - 291 WP_000667954.1 hypothetical protein -
QOR71_RS06565 1284182..1284571 - 390 WP_000048071.1 DUF5945 family protein -
QOR71_RS06570 1284568..1284795 - 228 WP_000110923.1 DUF5965 family protein -
QOR71_RS06575 1284849..1285925 - 1077 WP_000196866.1 toprim domain-containing protein -
QOR71_RS06580 1285965..1286603 - 639 WP_000933069.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(28-215)

Antitoxin

Cro/C1-type helix-turn-helix domain

(3-60)


Sequences

Toxin        


Download         Length: 259 a.a.        Molecular weight: 29308.16 Da        Isoelectric Point: 5.4232

>T297050 WP_000418077.1 NZ_OX461103:c1283297-1282521 [Streptococcus agalactiae]
MELEAFSQTDFDLALKRSIRSLTRGKTFSTNPQAILLGGQSGAGKTTIHRIKQKEFQGNIIIIDGDSYHSLHPNYLTLQE
KYGKGSVDYTKDFAGKMVEHLVDELSKQGYHLLIEGTLRTTQVPRQTAQLLASKEYQVSLAVIGTKTELSYLSTLIRYEE
LYTIDPNQARATPKELHDGIVEHLVDNLRELEDACLFDQIKIYQRDRLCVYDSETDEGSAADVLQECLFGKWSKVEEEML
KVGQERLREMVKRSGNDV

Download         Length: 777 bp

Antitoxin


Download         Length: 159 a.a.        Molecular weight: 18177.57 Da        Isoelectric Point: 4.3387

>AT297050 WP_000578852.1 NZ_OX461103:c1283773-1283297 [Streptococcus agalactiae]
MIGENIKSLRRTHDLTQPEFAKMVGISRNSLSRYENGTSTVSTELIDRICQKFNVSYVDIVGEDKMLTPVEDYQLTLKVE
VIKERGAAILSKLYRYQDSQDIAFDDESNPWILMSDDLAELINTKIYLVDTFDEIERYNGYLDGIERMLELASHQVVA

Download         Length: 477 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References