Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 240586..241198 Replicon chromosome
Accession NZ_OX460985
Organism Streptococcus agalactiae isolate MRI Z2-307

Toxin (Protein)


Gene name parE Uniprot ID Q8E7D3
Locus tag QOR59_RS01400 Protein ID WP_000384859.1
Coordinates 240586..240921 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID Q8E7D2
Locus tag QOR59_RS01405 Protein ID WP_000259017.1
Coordinates 240911..241198 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOR59_RS01375 235784..236425 + 642 WP_000591144.1 hypothetical protein -
QOR59_RS01380 236725..237600 + 876 WP_000421240.1 hypothetical protein -
QOR59_RS01385 237636..238070 + 435 WP_001220479.1 hypothetical protein -
QOR59_RS01390 238387..239643 + 1257 WP_000122836.1 MobV family relaxase -
QOR59_RS01395 239811..240281 + 471 WP_000130119.1 hypothetical protein -
QOR59_RS01400 240586..240921 - 336 WP_000384859.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOR59_RS01405 240911..241198 - 288 WP_000259017.1 hypothetical protein Antitoxin
QOR59_RS01410 241706..241996 + 291 WP_000078282.1 WXG100 family type VII secretion target -
QOR59_RS01415 242098..242505 + 408 WP_000749955.1 hypothetical protein -
QOR59_RS01420 242505..243092 + 588 WP_011074703.1 hypothetical protein -
QOR59_RS01425 243038..243716 + 679 Protein_228 hypothetical protein -
QOR59_RS01430 243701..244087 + 387 WP_000259072.1 hypothetical protein -
QOR59_RS01435 244121..244402 + 282 WP_000052404.1 hypothetical protein -
QOR59_RS01440 245245..246105 + 861 WP_000471421.1 Rgg/GadR/MutR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13296.98 Da        Isoelectric Point: 4.6565

>T297044 WP_000384859.1 NZ_OX460985:c240921-240586 [Streptococcus agalactiae]
MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIINDIEKLEVFPEVGFDADEKYGSEISNYHSTRGYTLSKD
YIVLYHIEEEENRVVIDYLLPTRSDYMKLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10906.50 Da        Isoelectric Point: 4.7271

>AT297044 WP_000259017.1 NZ_OX460985:c241198-240911 [Streptococcus agalactiae]
MVTVEKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKEKLFKQFQAEISKNIEDVRQ
GKFYTSEEVRAELGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A076Z4V6

References