Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4185683..4186363 Replicon chromosome
Accession NZ_OX460963
Organism Hafnia paralvei strain MIP2461 isolate MIP2461

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag QOT00_RS19445 Protein ID WP_283648133.1
Coordinates 4185683..4186003 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag QOT00_RS19450 Protein ID WP_283648134.1
Coordinates 4186040..4186363 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT00_RS19430 4181164..4182297 - 1134 WP_064572704.1 pentaheme c-type cytochrome TorC -
QOT00_RS19435 4182488..4183963 + 1476 WP_283648131.1 PLP-dependent aminotransferase family protein -
QOT00_RS19440 4184733..4185569 - 837 WP_283648132.1 DUF4942 domain-containing protein -
QOT00_RS19445 4185683..4186003 - 321 WP_283648133.1 TA system toxin CbtA family protein Toxin
QOT00_RS19450 4186040..4186363 - 324 WP_283648134.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QOT00_RS19455 4186376..4186846 - 471 WP_283648135.1 DNA repair protein RadC -
QOT00_RS19460 4186917..4187735 - 819 WP_283648136.1 DUF932 domain-containing protein -
QOT00_RS19465 4187885..4188682 - 798 WP_283648137.1 hypothetical protein -
QOT00_RS19470 4189126..4190010 - 885 WP_283648138.1 50S ribosome-binding GTPase -
QOT00_RS19475 4190102..4190923 - 822 WP_283648139.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12112.80 Da        Isoelectric Point: 5.9559

>T297035 WP_283648133.1 NZ_OX460963:c4186003-4185683 [Hafnia paralvei]
MHTSTVPATVPVSSRLPPVQVWQQLLTYLLEHHYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQEQTPFLTAIDILRARRATGLMNI

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12050.81 Da        Isoelectric Point: 6.7057

>AT297035 WP_283648134.1 NZ_OX460963:c4186363-4186040 [Hafnia paralvei]
MSFTSPHEWGLLSDITPRFGARLVQEGNRLYYLADRAGFTGSFSPIHLKKLDLAFPLFVEQLEDMLRAGELNPHQQRQVT
IQLASVTCIADTRGSCGYVYISIYPTL

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References