297028

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-KacA/DUF1778(antitoxin)
Location 2477097..2477894 Replicon chromosome
Accession NZ_OX460963
Organism Hafnia paralvei strain MIP2461 isolate MIP2461

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag QOT00_RS11740 Protein ID WP_096080816.1
Coordinates 2477370..2477894 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID A0A2A2MFP5
Locus tag QOT00_RS11735 Protein ID WP_039186676.1
Coordinates 2477097..2477366 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT00_RS11720 2472690..2473721 - 1032 WP_020303739.1 Mal regulon transcriptional regulator MalI -
QOT00_RS11725 2474003..2475598 + 1596 WP_039186680.1 maltose/glucose-specific PTS transporter subunit IIBC -
QOT00_RS11730 2475686..2476861 + 1176 WP_061060038.1 MalY/PatB family protein -
QOT00_RS11735 2477097..2477366 + 270 WP_039186676.1 DUF1778 domain-containing protein Antitoxin
QOT00_RS11740 2477370..2477894 + 525 WP_096080816.1 GNAT family N-acetyltransferase Toxin
QOT00_RS11745 2478076..2479074 + 999 WP_008813542.1 adenosine deaminase -
QOT00_RS11750 2479683..2480681 - 999 WP_008813543.1 bile acid:sodium symporter family protein -
QOT00_RS11755 2480813..2481856 - 1044 WP_283647840.1 oxidoreductase -
QOT00_RS11760 2482105..2482281 - 177 WP_283647841.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(8-85)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19687.55 Da        Isoelectric Point: 7.0494

>T297028 WP_096080816.1 NZ_OX460963:2477370-2477894 [Hafnia paralvei]
MPDLAIEIFSNDIEYDFAHFDCGEESLNIFLTNHLARQHNSRILRGYLLVTKEPKPKIVGYYTLSGSCFEKETLPSNTQK
RKVPYANVPSVTLGRLAIQKELQGQDWGTTLVTHAMKVIYHASLAVGIHGMFVDALNEKAKRFYLQLGFIALTGNNANSL
FYPTKSIEKLFEDE

Download         Length: 525 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10066.50 Da        Isoelectric Point: 7.0162

>AT297028 WP_039186676.1 NZ_OX460963:2477097-2477366 [Hafnia paralvei]
MSALKKQRIDLRLTDDDKSKIEEAAAMTNQTITQFMVASAAERAEEVIEQHRRLVLNDESWNLVMDAISNPPAPNSRLKR
AAKRLASME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2A2MFP5

References