Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 878856..879516 Replicon chromosome
Accession NZ_OX460963
Organism Hafnia paralvei strain MIP2461 isolate MIP2461

Toxin (Protein)


Gene name cptA Uniprot ID A0A2A2MBB6
Locus tag QOT00_RS04125 Protein ID WP_008815043.1
Coordinates 879103..879516 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2A2MBZ0
Locus tag QOT00_RS04120 Protein ID WP_008815042.1
Coordinates 878856..879122 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT00_RS04105 875035..875919 + 885 WP_004846922.1 nucleoside-specific channel-forming protein Tsx -
QOT00_RS04110 876123..876947 + 825 WP_283647553.1 shikimate 5-dehydrogenase -
QOT00_RS04115 877495..878481 - 987 WP_283647554.1 tRNA-modifying protein YgfZ -
QOT00_RS04120 878856..879122 + 267 WP_008815042.1 FAD assembly factor SdhE Antitoxin
QOT00_RS04125 879103..879516 + 414 WP_008815043.1 protein YgfX Toxin
QOT00_RS04130 879565..880083 - 519 WP_283647555.1 flavodoxin FldB -
QOT00_RS04135 880287..881186 + 900 WP_061059194.1 site-specific tyrosine recombinase XerD -
QOT00_RS04140 881215..881931 + 717 WP_061059193.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QOT00_RS04145 881937..883670 + 1734 WP_283647556.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16260.00 Da        Isoelectric Point: 9.1742

>T297026 WP_008815043.1 NZ_OX460963:879103-879516 [Hafnia paralvei]
VDQWRCDVRVSWRTQLLLLVTHGTLVLLILLAPWPENYSIYWLILLTLVVFESIRSQKQIAKVQGELNFLAENRISWQHQ
EWELCKTPWISDFGALLPLKSLKDQDKRKRLWIAADSLTPEAWSHLRRSLMQMRHDA

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10447.94 Da        Isoelectric Point: 5.5601

>AT297026 WP_008815042.1 NZ_OX460963:878856-879122 [Hafnia paralvei]
MDIENKSRIHWACRRGMRELDISIMPFFEHEYDSLSDTDKQTFVRLLECDDPDLFNWLMNHGSPKDPELAHMVKLIQTRN
KDRGPMAL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A2MBB6

Antitoxin

Source ID Structure
AlphaFold DB A0A2A2MBZ0

References