Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 743288..743970 Replicon chromosome
Accession NZ_OX460963
Organism Hafnia paralvei strain MIP2461 isolate MIP2461

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag QOT00_RS03505 Protein ID WP_283647537.1
Coordinates 743629..743970 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QOT00_RS03500 Protein ID WP_283647536.1
Coordinates 743288..743608 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOT00_RS03460 738846..739685 + 840 WP_283647530.1 DUF932 domain-containing protein -
QOT00_RS03465 739887..740591 + 705 WP_283647531.1 WYL domain-containing protein -
QOT00_RS03470 740588..741202 + 615 WP_283647532.1 hypothetical protein -
QOT00_RS03475 741292..741702 + 411 WP_283647533.1 hypothetical protein -
QOT00_RS03480 741779..741994 + 216 Protein_662 DUF905 domain-containing protein -
QOT00_RS03485 742090..742548 + 459 WP_283647534.1 antirestriction protein -
QOT00_RS03490 742557..743039 + 483 WP_283647535.1 DNA repair protein RadC -
QOT00_RS03495 743048..743269 + 222 WP_023233115.1 DUF987 domain-containing protein -
QOT00_RS03500 743288..743608 + 321 WP_283647536.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QOT00_RS03505 743629..743970 + 342 WP_283647537.1 TA system toxin CbtA family protein Toxin
QOT00_RS03510 744383..744895 + 513 WP_283647538.1 hypothetical protein -
QOT00_RS03515 745210..745413 + 204 Protein_669 DUF4942 domain-containing protein -
QOT00_RS03525 745719..746213 + 495 WP_008814957.1 G/U mismatch-specific DNA glycosylase -
QOT00_RS03530 746281..748113 - 1833 WP_004846659.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 729307..744895 15588


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(6-105)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12913.87 Da        Isoelectric Point: 9.0116

>T297025 WP_283647537.1 NZ_OX460963:743629-743970 [Hafnia paralvei]
MKTLPATISRATKPCLSHVAVWQMLLTRLLEQHYGLTLNNTPFSDETVIQEHIDAGITLADAVNFLVEKYELVRIDRRGF
SWQEQSPYLRAVDILRARQATGLLRRSHNNAVL

Download         Length: 342 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12057.61 Da        Isoelectric Point: 6.9464

>AT297025 WP_283647536.1 NZ_OX460963:743288-743608 [Hafnia paralvei]
MRSNVTWGLQRDTTPRLGARLVQEGNQLHYLADRASITGKFSDTECRKLDETFPHFISQMESMLTTGEMNPRHAHCVILY
HNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References