Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3267041..3267666 Replicon chromosome
Accession NZ_OX460951
Organism Morganella morganii strain HIS2824 isolate HIS2824

Toxin (Protein)


Gene name Hha Uniprot ID A0A0A2RCL2
Locus tag QOS63_RS15590 Protein ID WP_024474604.1
Coordinates 3267463..3267666 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QOS63_RS15585 Protein ID WP_046893178.1
Coordinates 3267041..3267400 (+) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS63_RS15575 3262095..3263288 + 1194 WP_046893180.1 efflux RND transporter periplasmic adaptor subunit -
QOS63_RS15580 3263303..3266479 + 3177 WP_046893179.1 efflux RND transporter permease subunit -
QOS63_RS15585 3267041..3267400 + 360 WP_046893178.1 Hha toxicity modulator TomB Antitoxin
QOS63_RS15590 3267463..3267666 + 204 WP_024474604.1 HHA domain-containing protein Toxin
QOS63_RS15600 3268555..3269418 + 864 WP_046893176.1 acyl-CoA thioesterase II -
QOS63_RS15605 3269479..3270768 - 1290 WP_052926736.1 ammonium transporter AmtB -
QOS63_RS15610 3270788..3271126 - 339 WP_046893175.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-113)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8073.39 Da        Isoelectric Point: 6.9770

>T297022 WP_024474604.1 NZ_OX460951:3267463-3267666 [Morganella morganii]
MTKLDYLMRLRKCTSIETLERVIEKNKYELTDDELEVFYSAADHRLAELTMNKLYDKIPASVWKFVR

Download         Length: 204 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13840.57 Da        Isoelectric Point: 4.2870

>AT297022 WP_046893178.1 NZ_OX460951:3267041-3267400 [Morganella morganii]
MDEYSPRNYDIAVLKYLCDELCREGTQTLIRSNNFWVNDLASDSNLKLNELLGYIADVTWSFKIKHTQNKDLISFVDEYI
DETYALFGQMEVSFNDVEEWKKMASLVSSMLTSEGHLVH

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A2RCL2

Antitoxin

Source ID Structure

References