Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 480451..480953 Replicon chromosome
Accession NZ_OX460951
Organism Morganella morganii strain HIS2824 isolate HIS2824

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QOS63_RS02120 Protein ID WP_046894051.1
Coordinates 480451..480705 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QOS63_RS02125 Protein ID WP_046894052.1
Coordinates 480702..480953 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS63_RS02095 475538..475681 - 144 WP_155402968.1 hypothetical protein -
QOS63_RS02100 475690..476349 - 660 WP_046894048.1 YtjB family periplasmic protein -
QOS63_RS02105 476451..477428 + 978 WP_004242106.1 phosphoserine phosphatase -
QOS63_RS02110 477454..478842 + 1389 WP_046894049.1 DNA repair protein RadA -
QOS63_RS02115 478858..480120 + 1263 WP_046894050.1 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR -
QOS63_RS02120 480451..480705 - 255 WP_046894051.1 Txe/YoeB family addiction module toxin Toxin
QOS63_RS02125 480702..480953 - 252 WP_046894052.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
QOS63_RS02130 481091..482758 - 1668 WP_046894053.1 energy-dependent translational throttle protein EttA -
QOS63_RS02135 482788..484089 - 1302 WP_046894054.1 DUF3596 domain-containing protein -
QOS63_RS02140 484082..484372 - 291 WP_283623349.1 excisionase family protein -
QOS63_RS02145 484405..484953 - 549 WP_283624154.1 3'-5' exonuclease -
QOS63_RS02150 484967..485167 - 201 WP_025152948.1 hypothetical protein -
QOS63_RS02155 485164..485601 - 438 WP_283624155.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 478858..540483 61625


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10023.35 Da        Isoelectric Point: 10.0255

>T297019 WP_046894051.1 NZ_OX460951:c480705-480451 [Morganella morganii]
MTLTFSSQAWEDYLYWQNTDKKTLRRINELIKAAQRTPFSGIGKPETLKNNLSGWWSRRITEEHRLVYRVTNQGVEVAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9433.77 Da        Isoelectric Point: 4.7863

>AT297019 WP_046894052.1 NZ_OX460951:c480953-480702 [Morganella morganii]
MKTLTYSEVRQNLTAAMNETVDDRIPILITRQKGTACVLLSLDEYQSLEETAYLMRSPNNARRLMDSIDELNAGKGLKKE
INE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References