Detailed information of TA system
Overview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 1325540..1326972 | Replicon | chromosome |
Accession | NZ_OX460941 | ||
Organism | Streptococcus agalactiae isolate MRI Z2-304 |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | - |
Locus tag | QOR58_RS06905 | Protein ID | WP_283571615.1 |
Coordinates | 1326127..1326972 (+) | Length | 282 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | - |
Locus tag | QOR58_RS06900 | Protein ID | WP_000037245.1 |
Coordinates | 1325540..1326130 (+) | Length | 197 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QOR58_RS06900 | 1325540..1326130 | + | 591 | WP_000037245.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
QOR58_RS06905 | 1326127..1326972 | + | 846 | WP_283571615.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
QOR58_RS06910 | 1327035..1329836 | - | 2802 | WP_283571616.1 | phage tail tip lysozyme | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1276678..1352023 | 75345 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 282 a.a. Molecular weight: 32476.07 Da Isoelectric Point: 4.9373
>T297015 WP_283571615.1 NZ_OX460941:1326127-1326972 [Streptococcus agalactiae]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVEQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFEKIIELLERFKSDT
IQNKQWQNYSKKYSYTKGISLTDVLDEMIHLIAVLISINSD
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVEQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFEKIIELLERFKSDT
IQNKQWQNYSKKYSYTKGISLTDVLDEMIHLIAVLISINSD
Download Length: 846 bp
Antitoxin
Download Length: 197 a.a. Molecular weight: 23268.93 Da Isoelectric Point: 8.3396
>AT297015 WP_000037245.1 NZ_OX460941:1325540-1326130 [Streptococcus agalactiae]
MSKKEILLEFIENHNGIITYKDCKALNIPTIYLTRLEKEGIIYRVEKGIFLTQNGDYDEYFFFQYRYPKAVFSYISALYL
QQFTDEIPQYFDITIPRGYRFNTPPANLNIHSVSKKYSELGITLVKTPMGNEVRVYDFERIICDFVIHREKIDTELFVKT
LQLYGNYPKKNLTKLYEYATKMNTLDKVKQTLEVLV
MSKKEILLEFIENHNGIITYKDCKALNIPTIYLTRLEKEGIIYRVEKGIFLTQNGDYDEYFFFQYRYPKAVFSYISALYL
QQFTDEIPQYFDITIPRGYRFNTPPANLNIHSVSKKYSELGITLVKTPMGNEVRVYDFERIICDFVIHREKIDTELFVKT
LQLYGNYPKKNLTKLYEYATKMNTLDKVKQTLEVLV
Download Length: 591 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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